Benvido ao repositorio institucional da Universidade de Santiago de Compostela.
A USC, sumándose ás iniciativas do Open Access, quere, mediante este repositorio, dar acceso á súas coleccións bibliográficas dixitalizadas e á produción investigadora e docente dos seus membros.

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Enantioenriched α-Vinyl 1,4-Benzodiazepines and 1,4-Benzoxazepines via enantioselective rhodium-catalyzed hydrofunctionalizations of alkynes and allenes
(ACS Publications, 2021)Benzofused seven-membered heterocycles such as 1,4-benzo[e]diazepines (1,4-BZDs) and 1,4-benzo[e]oxazepines (1,4-BZOs) were efficiently synthesized by Rh-catalyzed hydrofunctionalization of internal alkynes and allenes in ... -
Discovery of 3H-pyrrolo[2,3-c]quinolines with activity against Mycobacterium tuberculosis by allosteric inhibition of the glutamate-5-kinase enzyme
(Elsevier, 2022)The therapeutic potential of 3H-pyrrolo[2,3-c]quinolines—the main core of Marinoquinoline natural products—has been explored for the development of new anti-TB agents. The chemical modification of various positions in this ... -
A QIM-based evaluation of sensory quality of frozen–thawed roundnose grenadier (Coryphaenoides rupestris) and its applications
(ACS Publications, 2021)The quality index method (QIM) is widely used for fish sensory assessment, but there are hardly any studies on quality changes in fish that have been previously frozen. A QIM scheme was developed for frozen Roundnose ... -
Effect of the addition of different sodium alginates on viscoelastic, structural features and hydrolysis kinetics of corn starch gels
(Elsevier, 2022)Corn starch gels (1:4 w:w) were made with the addition (up to 2% w/w starch basis) of sodium alginates of different average molecular sizes and nature. Rheology of the starchy gels were characterized to evaluate their ... -
Potent and subtype-selective dopamine D2 receptor biased partial agonists discovered via an Ugi-based approach
(ACS Publications, 2021)Using a previously unexplored, efficient, and versatile multicomponent method, we herein report the rapid generation of novel potent and subtype-selective DRD2 biased partial agonists. This strategy exemplifies the search ...