Now showing items 1-3 of 3

    • A Functional Link between AMPK and Orexin Mediates the Effect of BMP8B on Energy Balance 

      Martins, Luís; Seoane-Collazo, Patricia; Contreras, Cristina; González-García, Ismael; Martínez Sánchez, Noelia; González, Francisco; Zalvide Torrente, Juan Bautista; Gallego, Rosalía; Diéguez González, Carlos; Nogueiras Pozo, Rubén; Tena-Sempere, Manuel; López, Miguel (Elsevier, 2016-08-11)
      AMP-activated protein kinase (AMPK) in the ventromedial nucleus of the hypothalamus (VMH) and orexin (OX) in the lateral hypothalamic area (LHA) modulate brown adipose tissue (BAT) thermogenesis. However, whether these two ...
    • High Levels of Receptor Tyrosine Kinases in CCM3-Deficient Cells Increase Their Susceptibility to Tyrosine Kinase Inhibition 

      Sartages García, Miriam; Floridia, Ebel; García Colomer, Mar; Iglesias García, Cristina; Macía Cortiñas, Manuel; Peñas Silva, Patricia; Couraud, Pierre-Olivier; Romero, Ignacio A.; Weksler, Babette; Pombo Ramos, Celia María; Zalvide Torrente, Juan Bautista (MDPI, 2020)
      Cerebral cavernous malformations (CCMs) are vascular malformations that can be the result of the deficiency of one of the CCM genes. Their only present treatment is surgical removal, which is not always possible, and an ...
    • The cerebral cavernous malformation 3 gene is necessary for senescence induction 

      Guerrero López, Ana; Iglesias García, Cristina; Raguz, Selina; Floridia, Ebel; Gil, Jesús; Pombo Ramos, Celia María; Zalvide Torrente, Juan Bautista (Wiley, 2015)
      Mutations in cerebral cavernous malformation 3 gene are knownto result in development of vascular malformations and haverecently been proposed to also give rise to meningiomas. Wereport in this study that lack of CCM3 ...

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