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    • Oncogenic D816V-KIT signaling in mast cells causes persistent IL-6 production 

      Tobío Ageitos, Araceli; Bandara, Geethani; Morris, Denise A.; Kim, Do-Kyun; O'Connell, Michael P.; Komarow, Hirsh D.; Carter, Melody C.; Smrz, Daniel; Metcalfe, Dean D.; Olivera, Ana (Ferrata Storti Foundation, 2019-04-02)
      Persistent dysregulation of IL-6 production and signaling have been implicated in the pathology of various cancers. In systemic mastocytosis, increased serum levels of IL-6 associate with disease severity and progression, ...





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