Now showing items 1-8 of 8

    • Central nicotine induces browning through hypothalamic κ opioid receptor 

      Seoane Collazo, Patricia; Liñares Pose, Laura; Rial Pensado, Eva; Romero Picó, Amparo; Moreno Navarrete, José María; Martínez Sánchez, Noelia; Garrido Gil, Pablo; Iglesias Rey, Ramón; Morgan, Donald A.; Tomasini, Naoki; Malone, Samuel Andrew; Senra, Ana; Folgueira Cobos, Cintia; Medina Gómez, Gema; Sobrino Moreiras, Tomás; Labandeira García, José Luis; Nogueiras Pozo, Rubén; Domingos, Ana I.; Fernández Real, José Manuel; Rahmouni, Kamal; Diéguez González, Carlos; López Pérez, Miguel Antonio (Nature Publishing Group, 2019)
      [ENG]Increased body weight is a major factor that interferes with smoking cessation. Nicotine, the main bioactive compound in tobacco, has been demonstrated to have an impact on energy balance, since it affects both feeding ...
    • Central nicotine induces browning through hypothalamic κ opioid receptor 

      Seoane Collazo, Patricia; Liñares Pose, Laura; Rial Pensado, Eva; Romero Picó, Amparo; Moreno Navarrete, José María; Martínez Sánchez, Noelia; Garrido Gil, Pablo; Iglesias Rey, Ramón; Morgan, Donald A.; Tomasini, Naoki; Malone, Samuel Andrew; Senra, Ana; Folgueira Cobos, Cintia; Medina Gómez, Gema; Sobrino Moreiras, Tomás; Labandeira García, José Luis; Nogueiras Pozo, Rubén; Domingos, Ana I.; Fernández Real, José Manuel; Rahmouni, Kamal; Diéguez González, Carlos; López Pérez, Miguel Antonio (Nature Publishing Group, 2019)
      [ENG]Increased body weight is a major factor that interferes with smoking cessation. Nicotine, the main bioactive compound in tobacco, has been demonstrated to have an impact on energy balance, since it affects both ...
    • Effects of Rho kinase inhibitors on grafts of dopaminergic cell precursors in a rat model of Parkinson's Disease 

      Rodríguez Pallares, Jannette; Rodríguez Pérez, Ana Isabel; Muñoz Patiño, Ana María; Parga Martín, Juan Andrés; Toledo Aral, Juan J.; Labandeira García, José Luis (Wiley, 2016)
      In models of Parkinson’s disease (PD), Rho kinase (ROCK) inhibitors have antiapoptotic and axonstabilizing effects on damaged neurons, decrease the neuroinflammatory response, and protect against dopaminergic neuron death ...
    • Functional Complexes of Angiotensin-Converting Enzyme 2 and Renin-Angiotensin System Receptors: Expression in Adult but Not Fetal Lung Tissue 

      Franco, Rafael; Lillo, Alejandro; Rivas Santisteban, Rafael; Rodríguez Pérez, Ana Isabel; Reyes Resina, Irene; Labandeira García, José Luis; Navarro, Gemma (MDPI, 2020)
      Angiotensin-converting enzyme 2 (ACE2) is a membrane peptidase and a component of the renin-angiotensin system (RAS) that has been found in cells of all organs, including the lungs. While ACE2 has been identified as the ...
    • Interaction between angiotensin type 1, type 2, and mas receptors to regulate adult neurogenesis in the brain ventricular–subventricular zone 

      García Garrote, María; Pérez Villalba, Ana; Garrido Gil, Pablo; Belenguer, Germán; Parga Martín, Juan Andrés; Pérez Sánchez, Francisco; Labandeira García, José Luis; Fariñas, Isabel; Rodríguez Pallares, Jannette (MDPI, 2019)
      The renin–angiotensin system (RAS), and particularly its angiotensin type-2 receptors (AT2), have been classically involved in processes of cell proliferation and maturation during development. However, the potential role ...
    • Involvement of PPAR-γ in the neuroprotective and anti-inflammatory effects of angiotensin type 1 receptor inhibition: effects of the receptor antagonist telmisartan and receptor deletion in a mouse MPTP model of Parkinson's disease 

      Garrido Gil, Pablo; Joglar, Belén; Rodríguez Pérez, Ana Isabel; Guerra Seijas, María Josefa Natividad; Labandeira García, José Luis (BioMED Central, 2012)
      Background: Several recent studies have shown that angiotensin type 1 receptor (AT1) antagonists such as candesartan inhibit the microglial inflammatory response and dopaminergic cell loss in animal models of Parkinson’s ...
    • Renin angiotensin system and gender differences in dopaminergic degeneration 

      Rodríguez Pérez, Ana Isabel; Valenzuela Limiñana, Rita; Joglar, Belén; Garrido Gil, Pablo; Guerra Seijas, María Josefa Natividad; Labandeira García, José Luis (BMC, 2011)
      Background: There are sex differences in dopaminergic degeneration. Men are approximately two times as likely as premenopausal women of the same age to develop Parkinson’s disease (PD). It has been shown that the local renin ...
    • The intracellular angiotensin system buffersdeleterious effects of the extracellular paracrine system 

      Villar Cheda, Begoña; Costa Besada, María Alicia; Valenzuela Limiñana, Rita; Pérez Costas, Emma; Meléndez Ferro, Miguel; Labandeira García, José Luis (Nature Publishing Group, 2017)
      The‘classical’renin–angiotensin system (RAS) is a circulating system that controls blood pressure. Local/paracrine RAS,identified in a variety of tissues, including the brain, is involved in different functions and diseases, ...





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