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    • SerpinA3N is a novel hypothalamic gene upregulated by a high-fat diet and leptin in mice 

      Sergi, Domenico; Campbell, Fiona M.; Grant, Christine; Morris, Amanda C.; Bachmair, Eva María; Koch, Christiane; McLean, Fiona H.; Muller, Aifric; Hoggard, Nigel; Roos, Baukje de; Porteiro Couto, Begoña; Boekschoten, Mark V.; McGillicuddy, Fiona C.; Kahn, Darcy; Nicol, Phyllis; Benzler, Jonas; Mayer, Claus-Dieter; Drew, Janice E.; Roche, Helen M.; Muller, Michael; Nogueiras Pozo, Rubén; Diéguez González, Carlos; Tups, Alexander; Williams, Lynda M. (BMC, 2018)
      Background Energy homeostasis is regulated by the hypothalamus but fails when animals are fed a high-fat diet (HFD), and leptin insensitivity and obesity develops. To elucidate the possible mechanisms underlying these ...





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