Browsing by Subject "Antibiotics"
Now showing items 1-13 of 13
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Adsorption of Tetracycline and Sulfadiazine onto Three Different Bioadsorbents in Binary Competitive Systems
(MDPI, 2021)Different antibiotics contained in manure, slurry, wastewater or sewage sludge are spread into the environment. The harmful effects of these antibiotics could be minimized by means of immobilization onto bioadsorbent ... -
Antibiotic Dispensation without a Prescription Worldwide: A Systematic Review
(MDPI, 2020)Antibiotic resistance still remains a major global public health problem and the dispensing of antibiotics without a prescription at community pharmacies is an important driver of this. MEDLINE, Pubmed and EMBASE databases ... -
Comparative Binding Energy (COMBINE) Analysis for Understanding the Binding Determinants of Type II Dehydroquinase Inhibitors
(Wiley, 2013-04-26)Herein we report comparative binding energy (COMBINE) analyses to derive quantitative structure–activity relationship (QSAR) models that help rationalize the determinants of binding affinity for inhibitors of type II ... -
Efficacy of Different Waste and By-Products from Forest and Food Industries in the Removal/Retention of the Antibiotic Cefuroxime
(MDPI, 2021)Environmental pollution due to antibiotics is a serious problem. In this work, the adsorption and desorption of the antibiotic cefuroxime (CFX) were studied in four by-products/residues from the forestry and food industries. ... -
Fast HPLC-MS/MS method for determining penicillin antibiotics in infant formulas using molecularly imprinted solid-phase extraction
(Hindawi, 2015)The dairy cattle may suffer from different infections relatively often, but the inflammation of the mammary gland is very important to the farmer. These infections are frequently treated with penicillin antimicrobial drugs. ... -
Freezing the Dynamic Gap for Selectivity: Motion‐Based Design of Inhibitors of the Shikimate Kinase Enzyme
(Wiley, 2016-10-04)Shikimate kinase (SK), the fifth enzyme of the aromatic amino acid biosynthesis, is a recognized target for antibiotic drug discovery. The potential of the distinct dynamic apolar gap, which isolates the natural substrate ... -
Impact of a multifaceted intervention to improve antibiotic prescribing: a pragmatic cluster-randomised controlled trial
(Springer Nature, 2020)Objectives This study sought to assess the effectiveness and return on investment (ROI) of a multifaceted intervention aimed at improving antibiotic prescribing for acute respiratory infections in primary care. Desig ... -
Las aguas residuales como reservorio y vehículo de transmisión de determinantes de resistencia a antibióticos
(2021-06)Los antibióticos se consideran uno de los grandes éxitos de la medicina del siglo XX. Sin embargo, su uso inadecuado y abuso han hecho que en la actualidad nos encontremos con un problema con graves consecuencias: la ... -
Low-dosage antibiotic intake can disturb gut microbiota in mice
(Taylor & Francis, 2018)The proportion of different microbial populations in gut microbiota (GM) is an important factor that in recent years has been linked to obesity and numerous metabolic diseases. Antibiotics are one of the factors that can ... -
Magnitude and determinants of antibiotic dispensing without prescription in Spain: a simulated patient study
(Oxford University Press, 2019)Objectives : Excessive and inappropriate use of antibiotics increases antimicrobial resistance. The aim of this study was to determine the magnitude and determinants of antibiotic dispensing without prescription in Spain ... -
Quality-by-design approach for the development of lipid-based nanosystems for anti-mycobacterial therapy
(2021)In this work, we rationally developed a lipid-based nanotechnological platform for hydrophobic anti-mycobacterial drugs. For this purpose, Artificial Intelligence tools were employed to assist formulation development, ... -
Recently developed synthetic compounds with anti-infective activity
(Elsevier, 2019)The ability of antibiotics to cure bacterial infections is at a serious risk due to the emergence and worldwide spread of superbugs. A lack of innovation and investment for almost 50 years has led to significant efforts ... -
Reducing the Flexibility of Type II Dehydroquinase for Inhibition: A Fragment‐Based Approach and Molecular Dynamics Study
(Wiley, 2017-09-19)A multidisciplinary approach was used to identify and optimize a quinazolinedione‐based ligand that would decrease the flexibility of the substrate‐covering loop (catalytic loop) of the type II dehydroquinase from Helicobacter ...