Now showing items 1-4 of 4

    • Biological Activities of Cyclic and Acyclic B-Type Laxaphycins in SH-SY5Y Human Neuroblastoma Cells 

      Alvariño Romero, Rebeca; Alonso López, Eva; Bornancin, Louis; Bonnard, Isabelle; Inguimbert, Nicolas; Banaigs, Bernard; Botana López, Luis Miguel (MDPI, 2020)
      Laxaphycins are a family of non-ribosomal lipopeptides that have been isolated from several cyanobacteria. Some of these compounds have presented cytotoxic activities, but their mechanism of action is poorly understood. ...
    • Targeting Multiple Signal Transduction Pathways of SARS-CoV-2: Approaches to COVID-19 Therapeutic Candidates 

      Fakhri, Sajad; Nouri, Zeinab; Moradi, Seyed Zachariah; Küpeli Akkol, Esra; Piri, Sana; Sobarzo Sánchez, Eduardo Marcelo; Farzaei, Mohammad Hosein; Echeverría, Javier (MDPI, 2021)
      Due to the complicated pathogenic pathways of coronavirus disease 2019 (COVID-19), related medicinal therapies have remained a clinical challenge. COVID-19 highlights the urgent need to develop mechanistic pathogenic ...
    • The cerebral cavernous malformation 3 gene is necessary for senescence induction 

      Guerrero López, Ana; Iglesias García, Cristina; Raguz, Selina; Floridia, Ebel; Gil, Jesús; Pombo Ramos, Celia María; Zalvide Torrente, Juan Bautista (Wiley, 2015)
      Mutations in cerebral cavernous malformation 3 gene are knownto result in development of vascular malformations and haverecently been proposed to also give rise to meningiomas. Wereport in this study that lack of CCM3 ...
    • Yessotoxin, a promising therapeutic tool 

      Alfonso Rancaño, María Amparo; Rodríguez Vieytes, María Mercedes; Botana López, Luis Miguel (MDPI, 2016-01-28)
      Yessotoxin (YTX) is a polyether compound produced by dinoflagellates and accumulated in filter feeding shellfish. No records about human intoxications induced by this compound have been published, however it is considered ...

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