Browsing by Subject "Carbenes"
Now showing items 1-8 of 8
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[2+1] Cycloaddition of Catalytic Ruthenium Vinyl Carbenes: A Stereoselective Controlled Access to (Z)- and (E)-Vinyl Epoxypyrrolidines
(American Chemical Society, 2016)Aza-alkynals undergo a cyclization reaction with diazo compounds in the presence of catalytic amounts of Cp*RuCl(cod) to afford vinyl epoxypyrrolidines, valuable building blocks for the synthesis of biologically active ... -
Cp*RuCl-Vinyl Carbenes: Two Faces and the Bifunctional Role in Catalytic Processes
(Wiley, 2020)Ruthenium vinyl carbenes derived from Cp/Cp*RuCl‐based complexes (Cp=cyclopentadiene, Cp*=1,2,3,4,5‐pentamethylcyclopentadiene) have been routinely invoked as key intermediates in tandem reactions involving a carbene/alkyne ... -
Cyclization by Catalytic Ruthenium Carbene Insertion into Csp3-H Bonds
(Wiley, 2011)A novel tandem Ru-catalyzed carbene addition to terminal alkynes/insertion of Csp3–H bonds in alkynyl acetals, ethers and amines has been accomplished under mild conditions. This cascade provides an efficient approach to ... -
Nucleophilic Addition of Amines to Ruthenium Carbenes: ortho‐(Alkynyloxy)benzylamine Cyclizations towards 1,3‐Benzoxazines
(Wiley, 2015)A new ruthenium-catalyzed cyclization of ortho-(alkynyloxy)benzylamines to dihydro-1,3-benzoxazines is reported. The cyclization is thought to take place via the vinyl ruthenium carbene intermediates that are easily formed ... -
Recent Advances in Ruthenium-Catalyzed Carbene/Alkyne Metathesis (CAM) Transformations
(Thieme, 2020)Carbene intermediates have shown versatile applications in modern synthetic chemistry. Catalytic ruthenium carbene/alkyne metathesis (CAM) with readily available substrates renders an efficient procedure for the in situ ... -
Ruthenium-Catalyzed Tandem Carbene/Alkyne Metathesis/N-H insertion. Synthesis of Benzofused Six-Membered Azaheterocycles
(American Chemical Society, 2020)Cp*RuCl-based catalyst enables the expedient access to a variety of benzofused six- membered azaheterocycles from unprotected o-alkynylanilines and trimethylsilyldiazomethane through an unprecedent tandem carbene/alkyne ... -
Vinyl Dihydropyrans and Dihydrooxazines: Cyclizations of Catalytic Ruthenium Carbenes Derived from Alkynals and Alkynones
(Wiley, 2014)A novel synthesis of 2‐vinyldihydropyrans and dihydro‐1,4‐oxazines (morpholine derivatives) from alkynals and alkynones has been developed. The cyclizations require a mild generation of catalytic ruthenium carbenes from ... -
Vinyl Ruthenium Carbenes: Valuable Intermediates in Catalysis
(Springer, 2017)Vinyl ruthenium carbenes are easily prepared from the neutral Ru(II) complex Cp*RuCl(cod) in the presence of functionalized alkynes and diazoalkanes. These intermediates have been proposed for several transformations in ...