Browsing by Subject "Cycloaddition"
Now showing items 1-11 of 11
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Concise, enantioselective, and versatile synthesis of (−)-Englerin A Based on a platinum-catalyzed [4C+3C] cycloaddition of allenedienes
(WILEY-VCH Verlag GmbH, 2016-10-13)A practical synthesis of (−)-englerin A was accomplished in 17 steps and 11 % global yield from commercially available achiral precursors. The key step consists of a platinum-catalyzed [4C+3C] allenediene cycloaddition ... -
Enantioselective Palladium-Catalyzed [3C + 2C] and [4C + 3C] Intramolecular Cycloadditions of Alkylidenecyclopropanes
(American Chemical Society, 2018-06-04)We report a highly enantioselective [3C + 2C] intramolecular cycloaddition of alkylidenecyclopropanes (ACPs) and alkenes. The best results are obtained by using sterically demanding chiral phosphoramidite ligands derived ... -
Gold(I)-Catalyzed Enantioselective [2+2+2] Cycloadditions: An Expedient Entry to Enantioenriched Tetrahydropyran Scaffolds
(American Chemical Society, 2017-02-22)A straightforward and atom-economical enantioselective approach to highly substituted tetrahydropyrans is reported. The process, which consists of an intermolecular gold-catalyzed [2+2+2] cycloaddition between allenamides, ... -
Gold(I)-catalyzed enantioselective cycloaddition reactions
(Beilstein-Institut, 2013)In recent years there have been extraordinary developments of gold(I)-catalyzed enantioselective processes. This includes progress in the area of cycloaddition reactions, which are of particular interest due to their ... -
Gold(I)-Catalyzed Intermolecular Cycloaddition of Allenamides with α,β-Unsaturated Hydrazones: Efficient Access to Highly Substituted Cyclobutanes
(American Chemical Society, 2014-11-19)α,β-Unsaturated N,N-dialkyl hydrazones undergo a mild [2 + 2] cycloaddition to allenamides when treated with a suitable gold catalyst. The method, which represents the first application of N,N-dialkyl hydrazones in gold ... -
Gold(I)‐Catalyzed Intermolecular [2+2] Cycloadditions between Allenamides and Alkenes
(Wiley, 2012)3‐(Propa‐1,2‐dien‐1‐yl)oxazolidin‐2‐one works as an efficient two‐carbon partner in a variety of intermolecular gold‐catalyzed [2+2] cycloadditions to alkenes. The transformation represents a simple and practical entry to ... -
Highly Enantioselective Cobalt‐Catalyzed (3+2) Cycloadditions of Alkynylidenecyclopropanes
(Wiley, 2021)Low‐valent cobalt complexes equipped with chiral ligands can efficiently promote highly enantioselective (3+2) cycloadditions of alkyne‐tethered alkylidenecyclopropanes. The annulation allows to assemble bicyclic systems ... -
Metal-Catalyzed annulations through activation and cleavage of C−H bonds
(WILEY-VCH Verlag GmbH, 2016-06-22)The exponential increase in the number of catalytic transformations that involve a metal-promoted activation of hitherto considered inert C−H bonds is promoting a fundamental change in the field of synthetic chemistry. ... -
Palladium(II)-Catalyzed annulation between ortho-alkenylphenols and allenes. Key role of the metal geometry in determining the reaction outcome
(American Chemical Society, 2016-04-14)2-Alkenylphenols react with allenes, upon treatment with catalytic amounts of Pd(II) and Cu(II), to give benzoxepine products in high yields and with very good regio- and diastereoselectivities. This contrasts with the ... -
Pd-Catalyzed (3 + 2) Heterocycloadditions between Alkylidenecyclopropanes and Carbonyls: Straightforward Assembly of Highly Substituted Tetrahydrofurans
(American Chemical Society, 2020)A Pd catalyst made from a Pd(0) source and a bulky biaryl phosphine ligand promotes highly efficient intramolecular (3 + 2) heterocycloadditions between alkylidenecyclopropanes (ACPs) and carbonyls. The annulations provide ... -
Transition Metal Promoted Transformations of Alkylidenecyclopropanes
(2020)Esta tesis doctoral explora la reactividad de los alquilidenciclopropanos (APCs) con distintos metales de transición. En el capítulo 1, se describe el desarrollo de variables enantioselectivas de las reacciones de cicloadición ...