Now showing items 1-10 of 10

    • Changes in epigenetic profiles throughout early childhood and their relationship to the response to pneumococcal vaccination 

      Pischedda, Sara; O’Connor, Daniel; Fairfax, Benjamin; Salas Ellacuriaga, Antonio; Martinón Torres, Federico; Pollard, Andrew J.; Trück, Johannes (Springer Nature, 2021)
      Background: Pneumococcal infections are a major cause of morbidity and mortality in young children and immaturity of the immune system partly underlies poor vaccine responses seen in the young. Emerging evidence suggests ...
    • A common epigenetic clock from childhood to old age 

      Freire Aradas, Ana María; Girón-Santamaría, Lorena; Mosquera Miguel, Ana; Ambroa Conde, Adrián; Phillips, Christopher Paul; Casares de Cal, María Ángeles; Gómez Tato, Antonio; Álvarez Dios, José Antonio; Aliferi, Anastasia; syndercombe court, denise; Branicki, Wojciech; Laréu, Maviky Victoria (Elsevier, 2022)
      Forensic age estimation is a DNA intelligence tool that forms an important part of Forensic DNA Phenotyping. Criminal cases with no suspects or with unsuccessful matches in searches on DNA databases; human identification ...
    • Dientes para la estimación de la edad 

      Triñanes Ozores, Jorge (2021)
      La estimación de la edad es un parámetro muy valioso en el campo forense, que puede ser inferido a partir del ADN procedente de diversos tejidos biológicos. Tanto la genética forense como la antropología forense trabajan ...
    • DNA methylation changes in fibromyalgia suggest the role of the immune-inflammatory response and central sensitization 

      GERRA, MARIA CARLA; Carnevali, Davide; Ossola, Paolo; González-Villar, Alberto J.; Pedersen, Inge Søkilde; Triñanes, Yolanda; Donnini, Claudia; manfredini, matteo; Arendt-Nielsen, Lars; Carrillo de la Peña, María Teresa; Gerra, Maria Carla (MDPI, 2021)
      Fibromyalgia (FM) has been explained as a result of gene-environment interactions. The present study aims to verify DNA methylation differences in eleven candidate genome regions previously associated to FM, evaluating ...
    • DNA methylation changes in genes involved in inflammation and depression in fibromyalgia: a pilot study 

      GERRA, MARIA CARLA; Carnevali, Davide; Pedersen, Inge Søkilde; Donnini, Claudia; manfredini, matteo; González-Villar, Alberto J.; Triñanes, Yolanda; Pidal Miranda, Marina; Arendt-Nielsen, Lars; Carrillo de la Peña, María Teresa (De Gruyter, 2021)
      Objectives: The present pilot study aims to investigate DNA methylation changes of genes related to fibromyalgia (FM) development and its main comorbid symptoms, including sleep impairment, inflammation, depression and ...
    • Molecular basis of intraspecific differentiation for heavy metal tolerance in the copper moss Scopelophila cataractae 

      Boquete Seoane, María Teresa; Schmid, Marc W; Wagemaker, niels; Carey, Sarah B.; McDaniel, Stuart; Richards, Christina; Alonso, Conchita (Elsevier, 2022)
      The remarkable capacity of bryophytes to tolerate extremely challenging abiotic conditions allows us to enhance our understanding of the diversity of molecular mechanisms involved in plant stress response. Here, we used ...
    • Novel SFRP2 DNA Methylation Profile Following Neoadjuvant Therapy in Colorectal Cancer Patients with Different Grades of BMI 

      Cabrera Mulero, Amanda; Crujeiras Martínez, Ana Belén; González Izquierdo, Andrea; Torres, Esperanza; Ayers, Duncan; Casanueva Freijo, Felipe; Tinahones Madueño, Francisco José; Morcillo, Sonsoles; Macías González, Manuel (MDPI, 2019)
      The relationship between body weight and different cancers is now well-recognized and among such cancers, colorectal cancer (CRC) is reported most frequently. Our group recently published findings, through an epigenome-wide ...
    • Salivary DNA Methylation as an Epigenetic Biomarker for Head and Neck Cancer. Part I: A Diagnostic Accuracy Meta-Analysis 

      Rapado González, Óscar; Martínez Reglero, Cristina; Salgado Barreiro, Ángel; Muinelo Romay, Laura; López López, Rafael; Muinelo Lorenzo, Juan; López López, Rafael; Díaz Lagares, Ángel; Suárez Cunqueiro, María Mercedes (MDPI, 2021)
      DNA hypermethylation is an important epigenetic mechanism for gene expression inactivation in head and neck cancer (HNC). Saliva has emerged as a novel liquid biopsy representing a potential source of biomarkers. We performed ...
    • Seed Dormancy: Molecular Control of Its Induction and Alleviation 

      Matilla Carro, Ángel Jesús (MDPI, 2020)
      A set of seed dormancy traits is included in this Special Issue. Thus, DELAY OF GERMINATION1 (DOG1) is reviewed in depth. Binding of DOG1 to Protein Phosphatase 2C ABSCISIC ACID (PP2C ABA) Hypersensitive Germination (AHG1) ...
    • Variability of multi-omics profiles in a population-based child cohort 

      Gallego-Paüls, Marta; Hernández Ferrer, Carles; Bustamante, Mariona; Basagaña, Xavier; Barrera-Gómez, Jose; Lau, Chung-Ho E.; Siskos, Alexandros; Vives-Usano, Marta; Ruiz-Arenas, Carlos; Wright, John P.; Wright, John; Slama, Rémy; Heude, Barbara; Casas, Maribel; Gražulevičieně, Regina; Chatzi, Leda; Borràs, Eva; Sabidó, Eduard; Carracedo Álvarez, Ángel María; Estivill, Xavier; Urquiza Ortiz, José Miguel; Coen, Muireann; Keun, Hector; González Ruiz, Juan Ramon; Vrijheid, Martine; Maitre, Léa (Nature Publishing Group, 2021)
      Background: Multiple omics technologies are increasingly applied to detect early, subtle molecular responses to environmental stressors for future disease risk prevention. However, there is an urgent need for further ...





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