Browsing by Subject "Epigenetics"
Now showing items 1-6 of 6
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Changes in epigenetic profiles throughout early childhood and their relationship to the response to pneumococcal vaccination
(Springer Nature, 2021)Background: Pneumococcal infections are a major cause of morbidity and mortality in young children and immaturity of the immune system partly underlies poor vaccine responses seen in the young. Emerging evidence suggests ... -
Differential expression of snoRNAs in oral squamous cell carcinomas: new potential diagnostic markers
(Taylor & Francis, 2018-01-26)Background: Small nucleolar RNAs (snoRNAs) are small non-coding RNA sequences whose most studied function is ribosome biogenesis. The altered expression of snoRNA is observed in tumoral processes such as breast cancer and ... -
Effects of Brassicaceae Isothiocyanates on Prostate Cancer
(MDPI, 2016-05-12)Despite the major progress made in the field of cancer biology, cancer is still one of the leading causes of mortality, and prostate cancer (PCa) is one of the most encountered malignancies among men. The effective management ... -
Epigenetic modulation of the immune system in early childhood: from infectious diseases to vaccines
(2021)Epigenetic mechanisms regulate gene expression and transcription in a dynamic way. Many functional differences observed in the immune system of neonates and adults seem to be associated with epigenetic modifications of ... -
Salivary DNA Methylation as an Epigenetic Biomarker for Head and Neck Cancer. Part I: A Diagnostic Accuracy Meta-Analysis
(MDPI, 2021)DNA hypermethylation is an important epigenetic mechanism for gene expression inactivation in head and neck cancer (HNC). Saliva has emerged as a novel liquid biopsy representing a potential source of biomarkers. We performed ... -
Transgenerational inheritance of chemical-induced signature: A case study with simvastatin
(Elsevier, 2020)The hypothesis that exposure to certain environmental chemicals during early life stages may disrupt reproduction across multiple non-exposed generations has significant implications for understanding disease etiology and ...