Now showing items 1-4 of 4

    • Changes in epigenetic profiles throughout early childhood and their relationship to the response to pneumococcal vaccination 

      Pischedda, Sara; O’Connor, Daniel; Fairfax, Benjamin; Salas Ellacuriaga, Antonio; Martinón Torres, Federico; Pollard, Andrew J.; Trück, Johannes (Springer Nature, 2021)
      Background: Pneumococcal infections are a major cause of morbidity and mortality in young children and immaturity of the immune system partly underlies poor vaccine responses seen in the young. Emerging evidence suggests ...
    • Differential expression of snoRNAs in oral squamous cell carcinomas: new potential diagnostic markers 

      Chamorro Petronacci, Cintia Micaela; Pérez-Sayáns García, Mario; Padín Iruegas, María Elena; Marichalar Mendia, Xabier; Gallas Torreira, Mercedes; García García, Abel (Taylor & Francis, 2018-01-26)
      Background: Small nucleolar RNAs (snoRNAs) are small non-coding RNA sequences whose most studied function is ribosome biogenesis. The altered expression of snoRNA is observed in tumoral processes such as breast cancer and ...
    • Effects of Brassicaceae Isothiocyanates on Prostate Cancer 

      Novío Mallón, Silvia; CARTEA, ELENA; Soengas, Pilar; Freire Garabal, Manuel; Núñez-Iglesias, María Jesús (MDPI, 2016-05-12)
      Despite the major progress made in the field of cancer biology, cancer is still one of the leading causes of mortality, and prostate cancer (PCa) is one of the most encountered malignancies among men. The effective management ...
    • Transgenerational inheritance of chemical-induced signature: A case study with simvastatin 

      Neuparth, Teresa; Machado, André M.; Montes Goyanes, Rosa María; Rodil Rodríguez, María del Rosario; Barros, Susana; Alves, Nelson; Ruivo, Raquel; Castro, Luis Filipe; Quintana Álvarez, José Benito; Santos, Miguel Machado (Elsevier, 2020)
      The hypothesis that exposure to certain environmental chemicals during early life stages may disrupt reproduction across multiple non-exposed generations has significant implications for understanding disease etiology and ...

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