Now showing items 1-4 of 4

    • Light-Controlled Cellular Internalization and Cytotoxicity of Nucleic Acid-Binding Agents: Studies in Vitro and in Zebrafish Embryos 

      Penas Tallón, Cristina; Sánchez López, Mateo Isidro; Guerra Varela, Jorge; Sánchez Piñón, Laura; Vázquez Sentís, Marco Eugenio; Mascareñas Cid, José Luis (Wiley, 2016)
      We synthesized octa‐arginine conjugates of DNA‐binding agents (bisbenzamidine, acridine and Thiazole Orange) and demonstrated that their DNA binding and cell internalization can be inhibited by appending a (negatively ...
    • Synthesis and Supramolecular Functional Assemblies of Ratiometric pH Probes 

      Méndez Ardoy, Alejandro; Reina Martín, Jose Juan; Montenegro García, Javier (Wiley, 2020)
      Tracking the pH with spatiotemporal resolution is a critical challenge for synthetic chemistry, chemical biology and beyond. Over the last decade different small probes and supramolecular systems have emerged for in celluloor ...
    • Towards Ratiometric Sensing of Amyloid Fibrils In Vitro 

      Freire Rodríguez, Sonia; Rodríguez Prieto, María de la Flor; Ríos Rodríguez, María del Carmen; Penedo Esteiro, Juan Carlos; Al-Soufi, Wajih; Novo Rodríguez, María de la Merced (Wiley, 2015)
      The aggregation of amyloid‐β peptide and its accumulation in the human brain has an important role in the etiology of Alzheimer’s disease. Thioflavin T has been widely used as a fluorescent marker for these amyloid aggregates. ...
    • Trending Topics on Coumarin and Its Derivatives in 2020 

      Carneiro Viqueira, Aitor; Matos, Maria João Correia Pinto Carvalho de; Uriarte Villares, Eugenio; Santana Penín, María Lourdes (MDPI, 2021)
      Coumarins are naturally occurring molecules with a versatile range of activities. Their structural and physicochemical characteristics make them a privileged scaffold in medicinal chemistry and chemical biology. Many ...





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