Now showing items 1-5 of 5

    • Changes in epigenetic profiles throughout early childhood and their relationship to the response to pneumococcal vaccination 

      Pischedda, Sara; O’Connor, Daniel; Fairfax, Benjamin; Salas Ellacuriaga, Antonio; Martinón Torres, Federico; Pollard, Andrew J.; Trück, Johannes (Springer Nature, 2021)
      Background: Pneumococcal infections are a major cause of morbidity and mortality in young children and immaturity of the immune system partly underlies poor vaccine responses seen in the young. Emerging evidence suggests ...
    • DNA methylation changes in fibromyalgia suggest the role of the immune-inflammatory response and central sensitization 

      GERRA, MARIA CARLA; Carnevali, Davide; Ossola, Paolo; González-Villar, Alberto J.; Pedersen, Inge Søkilde; Triñanes, Yolanda; Donnini, Claudia; manfredini, matteo; Arendt-Nielsen, Lars; Carrillo de la Peña, María Teresa; Gerra, Maria Carla (MDPI, 2021)
      Fibromyalgia (FM) has been explained as a result of gene-environment interactions. The present study aims to verify DNA methylation differences in eleven candidate genome regions previously associated to FM, evaluating ...
    • Los primeros 1000 días: una oportunidad para reducir la carga de las enfermedades no transmisibles 

      Moreno Villares, José Manuel; Collado, María Carmen; Larqué, Elvira; Leis Trabazo, María Rosaura; Sáenz de Pipaon, Miguel; Moreno Aznar, Luis A. (Arán Ediciones, 2019)
      El crecimiento y desarrollo de un individuo está determinado desde la etapa embrionaria por su genética y los factores ambientales con los que interactúa. Los riesgos para la salud infantil y adulta pueden programarse ...
    • Role of the IFN I system against the VHSV infection in juvenile Senegalese sole (Solea senegalensis) 

      Álvarez Torres, Daniel; Podadera, Ana M.; Bejar, Julia; Bandín Matos, María Isabel; Alonso, M. Carmen; García Rosado, Esther (BioMed Central, 2016)
      Senegalese sole is susceptible to marine VHSV isolates but is not affected by freshwater isolates, which may indicate differences regarding virus-host immune system interaction. IFN I induces an antiviral state in fish, ...
    • Yessotoxin, a promising therapeutic tool 

      Alfonso Rancaño, María Amparo; Rodríguez Vieytes, María Mercedes; Botana López, Luis Miguel (MDPI, 2016-01-28)
      Yessotoxin (YTX) is a polyether compound produced by dinoflagellates and accumulated in filter feeding shellfish. No records about human intoxications induced by this compound have been published, however it is considered ...





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