Browsing by Subject "NAFLD"
Now showing items 1-3 of 3
-
Adiposidad y carcinogénesis hepática: una aproximación epigenética
(2021)En síntesis, el trabajo realizado ha evidenciado que un exceso de adiposidad, vinculado a la manifestación de estrés oxidativo e inflamación, se asocia con la desregulación de genes implicados en la carcinogénesis, en ... -
Inhibition of ATG3 ameliorates liver steatosis by increasing mitochondrial function
(Elsevier, 2021)Non-alcoholic fatty liver disease (NAFLD) is a major health threat in both developed and developing countries and is a precursor of the more advanced liver diseases, including non-alcoholic steatohepatitis (NASH), cirrhosis, ... -
Neddylation inhibition ameliorates steatosis in NAFLD by boosting hepatic fatty acid oxidation via the DEPTOR-mTOR axis
(Elsevier, 2021)Objective: Neddylation is a druggable and reversible ubiquitin-like post-translational modification upregulated in many diseases, including liver fibrosis, hepatocellular carcinoma, and more recently, non-alcoholic fatty ...