Now showing items 1-4 of 4

    • Comprehensive genomic review of TCGA head and neck squamous cell carcinomas (HNSCC) 

      Pérez-Sayáns García, Mario; Chamorro Petronacci, Cintia Micaela; Lorenzo Pouso, Alejandro Ismael; Padín Iruegas, María Elena; Blanco Carrión, Andrés; Suárez Peñaranda, José Manuel; García García, Abel (MDPI, 2019)
      The aim of this present study was to comprehensively describe somatic DNA alterations and transcriptional alterations in the last extension of the HNSCC subsets in TCGA, encompassing a total of 528 tumours. In order to ...
    • Context-dependent impact of RAS oncogene expression on cellular reprogramming to pluripotency 

      Ferreirós López, Alba; Pedrosa, Pablo; Silva Álvarez, Sabela da; Triana Martínez, Francisco; Vilas Martínez, Jéssica María; Picallos Rabina, Pilar; González, Patricia; Gómez, María; Li, Han; García-Caballero Parada, Tomás; González Barcia, Miguel; Vidal Figueroa, Anxo; Collado, Manuel (Cell Press, 2019)
      Induction of pluripotency in somatic cells with defined genetic factors has been successfully used to investigate the mechanisms of disease initiation and progression. Cellular reprogramming and oncogenic transformation ...
    • Reprogramación celular y cáncer 

      Ferreirós López, Alba (2018)
      máticas hasta el estado pluripotente. El estudio de este proceso aporta información muy valiosa sobre la identidad celular y resulta de gran utilidad como herramienta para la investigación biomédica de distintas ...
    • Uncoupling Oncogene-Induced Senescence (OIS) and DNA Damage Response (DDR) triggered by DNA hyper-replication: lessons from primary mouse embryo astrocytes (MEA) 

      Seoane, Marcos; Costoya Puente, José Antonio; Arce Vázquez, Víctor Manuel (Springer Nature, 2017-10-11)
      Oncogene-induced senescence (OIS) is a complex process, in which activation of oncogenic signals during early tumorigenesis results in a high degree of DNA replication stress. The ensuing response to the DNA damage produces ...





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