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    • POU1F1 transcription factor induces metabolic reprogramming and breast cancer progression via LDHA regulation 

      Martínez Ordóñez, Anxo; Seoane Ruzo, Samuel; Ávila Concepción, Leandro; Eiró Díaz, Noemí; Macía Cortiñas, Manuel; Arias, Maria Efigenia; Pires Pereira, Fabio; García-Caballero, Tomas; González Lado, Noemi; Aguiar Fernández, Pablo; Vizoso, Francisco; Pérez Fernández, Román (Nature, 2021)
      Metabolic reprogramming is considered hallmarks of cancer. Aerobic glycolysis in tumors cells has been well-known for almost a century, but specific factors that regulate lactate generation and the effects of lactate in ...





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