Browsing by Subject "PDE10A inhibitors"

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    • Computer-aided design of multi-target ligands at A1R, A2AR and PDE10A, key proteins in neurodegenerative diseases 

      Kalash, Leen; Val García, Cristina; Azuaje Guerrero, Jhonny Alberto; Loza García, María Isabel; Svensson, Fredrik; Zoufir, Azedine; Mervin, Lewis; Ladds, Graham; Brea Floriani, José Manuel; Glen, Robert; Sotelo Pérez, Eddy; Bender, Andreas (BioMed Central, 2017)
      Compounds designed to display polypharmacology may have utility in treating complex diseases, where activity at multiple targets is required to produce a clinical efect. In particular, suitable compounds may be useful in ...




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