Now showing items 1-3 of 3

    • Glycosylated Cell Penetrating Peptides, GCPPs 

      Gallego Gómez, Iván; Rioboo Vidal, Alicia; Reina, José J.; Díaz, Bernardo; Canales, Ángeles; Cañada, F. Javier; Guerra Varela, Jorge; Sánchez Piñón, Laura Elena; Montenegro García, Javier (Wiley, 2019-01-23)
      The cell membrane regulates the exchange of molecules and information with the external environment. However, this control barrier hinders the delivery of exogenous bioactive molecules that can be applied to correct cellular ...
    • Supramolecular Recognition and Selective Protein Uptake by Peptide Hybrids 

      Juanes Carrasco, Marisa; Lostalé Seijo, Irene; Granja Guillán, Juan Ramón; Montenegro García, Javier (Wiley, 2018-04-27)
      The intracellular transport of exogenous proteins has emerged as one of the most promising methodologies for biotechnology and chemical biology. Current protein delivery is mainly approached by liposome encapsulation, ...
    • Tuning the properties of penetrating peptides by oxime conjugation 

      Pazo Pascual, Marta; Fernández Caro, Héctor; Priegue Caamaño, Juan Manuel; Lostalé Seijo, Irene; Montenegro García, Javier (Georg Thieme Verlag, 2017-01-25)
      We here describe the application of oxime bond formation between a peptide scaffold and different aldehydes to modify the transporting capabilities of penetrating peptides. We show that bonds such as oximes offer a great ...

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