Now showing items 1-4 of 4

    • A New Pathway for Protein Haptenation by β‐Lactams 

      Pérez Ruiz, Raúl; Lence Quintana, Emilio José; Andreu, Inmaculada; Limones Herrero, Daniel; González Bello, Concepción; Miranda, Miguel A.; Jiménez, Consuelo M. (Wiley, 2017-08-09)
      The covalent binding of β‐lactams to proteins upon photochemical activation has been demonstrated by using an integrated approach that combines photochemical, proteomic and computational studies, selecting human serum ...
    • Ruthenation of Non‐stacked Guanines in DNA G‐Quadruplex Structures: Enhancement of c‐MYC Expression 

      Rodríguez Villar, Jéssica; Mosquera Mosquera, Jesús; Rodríguez Couceiro, José; Vázquez Sentís, Marco Eugenio; Mascareñas Cid, José Luis (Wiley, 2016)
      Guanine quadruplexes (GQs) are compact four‐stranded DNA structures that play a key role in the control of a variety of biological processes, including gene transcription. Bulky ruthenium complexes featuring a bipyridine, ...
    • Temporary Electrostatic Impairment of DNA Recognition: Light‐Driven DNA Binding of Peptide Dimers 

      Jiménez Balsa, Adrián; Pazos Chantrero, Elena; Martínez Albardonedo, Borja; Mascareñas Cid, José Luis; Vázquez Sentís, Marco Eugenio (Wiley, 2012)
      Appending negatively charged Glu8 tails to a peptide dimer derived from the GCN4 transcription factor leads to an effective suppression of its DNA binding. The specific DNA recognition can be restored by irradiation with ...
    • TiO2‐Based Photocatalysis at the Interface with Biology and Biomedicine 

      Tomás Gamasa, María; Mascareñas Cid, José Luis (Wiley, 2019)
      The conversion of sunlight into chemical energy by using photosynthetic machinery is at the heart of nature and life. Scientists have also learned to use light energy to promote a great variety of chemical reactions, most ...

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