Browsing by Author "Sotelo Pérez, Eddy"
Now showing items 1-2 of 2
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Desarrollo de Antagonistas selectivos del receptor A3 de Adenosina
Miranda Pastoriza, Darío (2020-11)El presente Trabajo de Fin de Grado describe el diseño, síntesis y evaluación farmacológica de derivados del sistema 1,4-dihidrobenzo[4,5]imidazo[1,2-a]pirimidina como antagonistas del receptor A3 de adenosina. Empleando ... -
New Ligands and Pharmacological Tools for the Study of G Protein-Coupled Receptors Using Multicomponent Reactions
Mallo Abreu, Ana (2021)This PhD thesis describes the synthesis and optimization of novel families of potent and selective A2B antagonists and D2 biased partial agonists, thus contributing to the discovery of therapeutic agents for the treatment ...