Browsing by Author "Universidade de Santiago de Compostela. Departamento de Farmacia e Tecnoloxía Farmacéutica"
Now showing items 1-18 of 18
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3D printed carboxymethyl cellulose scaffolds for autologous growth factors delivery in wound healing
Díaz Gómez, Luis Antonio; González Prada, Iago; Millán Lence, Rosendo; Silva Candal, Andrés da; Bugallo Casal, Ana; Campos Pérez, Francisco; Concheiro Nine, Ángel Joaquín; Álvarez Lorenzo, Carmen Isabel (Elsevier, 2022)This work aims to use carboxymethyl cellulose (CMC) as main structural and functional component of 3D printed scaffolds for healing of diabetic wounds. Differently from previous inks involving small contents in CMC, herein ... -
Blood glutamate EAAT2-cell grabbing therapy in cerebral ischemia
Pérez Mato, María; Iglesias Rey, Ramón; Vieites Prado, Alba; Dopico López, Antonio; Argibay González, Bárbara; Fernández Susavila, Héctor; Silva Candal, Andrés da; Pérez Díaz, Amparo; Correa Paz, Clara; Günther, Anne; Ávila Gómez, Paulo; Loza García, María Isabel; Baumann, Arnd; Castillo Sánchez, José Antonio; Sobrino Moreiras, Tomás; Campos Pérez, Francisco (Elsevier, 2019-01)Background Excitatory amino acid transporter 2 (EAAT2) plays a pivotal role in glutamate clearance in the adult brain, thereby preventing excitotoxic effects. Considering the high efficacy of EAAT2 for glutamate uptake, ... -
Chitosan and Kappa-Carrageenan Vaginal Acyclovir Formulations for Prevention of Genital Herpes. In Vitro and Ex Vivo Evaluation
Sánchez Sánchez, María Pilar; Martín Illana, Araceli; Ruiz Caro, Roberto; Bermejo, Paulina; Abad, María José; Carro, Rubén; Bedoya, Luis Miguel; Tamayo, Aitana; Rubio, Juan; Fernández Ferreiro, Anxo; Otero Espinar, Francisco Javier; Veiga, María Dolores (MDPI, 2015)Vaginal formulations for the prevention of sexually transmitted infections are currently gaining importance in drug development. Polysaccharides, such as chitosan and carrageenan, which have good binding capacity with ... -
Desarrollo de nuevos vehículos para la administración de vacunas genéticas
Csaba, Noemi Stefania (2005) -
Efecto de las ciclodextrinas sobre la cesión de fármacos en matrices de hidroxipropilmetilcelulosa
Pose Vilarnovo, Beatriz (2005) -
Exploring the efficiency of gallic acid-based dendrimers and their block copolymers with PEG as gene carriers
Fuente Freire, María de la; Raviña Fernández, Manuela; Sousa Hervés, Ana; Correa, Juan; Riguera Vega, Ricardo; Fernández Megía, Eduardo; Sánchez Barreiro, Alejandro; Alonso Fernández, María José (Future Science, 2012-07-20)The synthesis of a new family of amino-functionalized gallic acid-triethylene glycol (GATG) dendrimers and their block copolymers with polyethylene glycol (PEG) has recently being disclosed. In addition, these dendrimers ... -
In silico simulations and functional cell studies evidence similar potency and distinct binding of pacific and caribbean ciguatoxins
Raposo García, Sandra; Castro Alonso, David Miguel; Lence Quintana, Emilio José; Estévez Bastos, Pablo; Leão, José Manuel; González Bello, Concepción; Gago Martínez, Ana; Louzao Ojeda, María Carmen; Botana López, Luis Miguel (Springer, 2022)Ciguatoxins (CTX) cause ciguatera poisoning, which is the most common reported human food poisoning related to natural marine toxins. Pacific ciguatoxins are the most abundant and studied CTX analogues; however, the growing ... -
Ionic and Polyampholyte N-Isopropylacrylamide-Based Hydrogels Prepared in the Presence of Imprinting Ligands: Stimuli-Responsiveness and Adsorption/Release Properties
Lago Crespo, Miguel Ángel; Grinberg, Valerij Ya; Burova, Tatiana V.; Concheiro Nine, Ángel Joaquín; Álvarez Lorenzo, Carmen Isabel (MDPI, 2011)The conformation of the imprinted pockets in stimulus-responsive networks can be notably altered when the stimulus causes a volume phase transition. Such a tunable affinity for the template molecule finds interesting ... -
La Facultad de Farmacia de Santiago de Compostela (1900-1971)
Brasa Arias, Beatriz (2012-02-02)Este trabajo tiene por objetivo el estudio de la Facultad de Farmacia de Santiago de Compostela durante los más de setenta años del siglo XX que ocupó las instalaciones del Colegio de Fonseca. De esta memoria de tesis se ... -
Microsferas de polisacáridos y lípidos para la administración pulmonar de macromoléculas terapéuticas
Carrión Recio, Dayamí (2006) -
Nanocápsulas de quitosano : nuevos vehículos para el transporte de péptidos a través de la mucosa nasal e instestinal
Prego Rodríguez, Cecilia (2005)Los avances logrados en el campo de la biotecnología y de la ingeniería genética han permitido el creciente desarrollo de macromoléculas activas de naturaleza peptídica y proteica. A pesar del interesante potencial ... -
New insights into the causes of human illness due to consumption of azaspiracid contaminated shellfish
Chevallier, Olivier P.; Graham, S. F.; Alonso, E.; Duffy, C.; Silke, J.; Campbell, K.; Botana López, Luis Miguel; Elliot, Christopher T. (Nature Publishing Group, 2015)Azaspiracid (AZA) poisoning was unknown until 1995 when shellfish harvested in Ireland caused illness manifesting by vomiting and diarrhoea. Furtherin vivo/vitro studies showed neurotoxicity linked with AZA exposure. ... -
A new potential nano-oncological therapy based on polyamino acid nanocapsules
Gonzalo, Teresa; Lollo, Giovanna; García-Fuentes, Marcos; Torres, Dolores; Correa, Juan; Riguera Vega, Ricardo; Fernández Megía, Eduardo; Calvo, Pilar; Avilés, Pablo; Guillén, Maria José; Alonso Fernández, María José (Elsevier, 2013-07)A critical objective in cancer therapy is to reduce the systemic toxicity through the modification of the biodistribution of anticancer drugs. Herein, we disclose a new biodegradable nanocarrier, polyglutamic acid (PGA) ... -
Novel Hyaluronic Acid-Chitosan Nanoparticles for Ocular Gene Therapy
Fuente Freire, María de la; Seijo Rey, María Begoña; Alonso Fernández, María José (Arvo Journals, 2008)purpose. Gene therapy offers a promising alternative for the treatment of ocular diseases. However, the implementation of this type of therapy is actually hampered by the lack of an efficient ocular gene delivery carrier. ... -
Peletización de diferentes mezclas de almidones y sus derivados : caracterización mediante técnicas de análisis de imagen
Almeida Prieto, Sergio (2005) -
Pluronic®/casein micelles for ophthalmic delivery of resveratrol: in vitro, ex vivo, and in vivo tests
Vivero López, María; Sparacino, Chiara; Quelle Regaldie, Ana; Sánchez Piñón, Laura Elena; Candal Suárez, Eva María; Barreiro Iglesias, Antón; Huete Toral, Fernando; Carracedo Rodríguez, Juan Gonzalo (Elsevier, 2022)Ocular health may strongly benefit from the supply of antioxidant agents that counteract free radicals and reactive oxygen species responsible for long-term eye diseases. Additionally, natural antioxidants like resveratrol ... -
Polysaccharide-based aerogel microspheres for oral drug delivery
García González, Carlos Alberto; Jin, Ming; Gerth, J.; Álvarez Lorenzo, Carmen Isabel; Smirnova, I. (Elsevier, 2015-03-06)Polysaccharide-based aerogels in the form of microspheres were investigated as carriers of poorly water soluble drugs for oral administration. These bio-based carriers may combine the biocompatibility of polysaccharides ... -
Sistemas dispersos heteroxéneos: bases fisicoquímicas
Otero Espinar, Francisco Javier (Universidade de Santiago de Compostela. Servizo de Publicacións e Intercambio Científico, 2008)Cando un composto é soluble noutro podemos formar unha disolución verdadeira. Nesta, o soluto atópanse dispersado a nivel molecular no disolvente de maneira que as moléculas de disolvente e de soluto posúen tamaño similar, ...