Population aging has led to an increase in neurodegenerative illnesses prevalence worldwide, being Alzheimer’s disease the most common dementia. Currently, there are no treatments able to delay this pathology, so the search ...

Makaluvamines are pyrroloiminoquinones isolated from Zyzzya sponges. Until now, they have been described as topoisomerase II inhibitors with cytotoxic effects in diverse tumor cell lines. In the present work, seven ...