• A theoretical study of ternary indole–cation–anion complexes 

  Carrazana Iglesias, Jorge A.; Cabaleiro-Lago, Enrique M.; Campo Cacharrón, Alba; Rodríguez-Otero, Jesús (Royal Society of Chemistry, 2014-09-03)

  The simultaneous interactions of an anion and a cation with a π system were investigated by MP2 and M06-2X theoretical calculations. Indole was chosen as a model π system for its relevance in biological environments. Two ...

• Synthetic materials at the forefront of gene delivery 

  Lostalé-Seijo, Irene; Montenegro, Javier (Springer Nature, 2018-09-21)

  The delivery of nucleic acids with transient activity for genetic engineering is a promising methodology with potential applications in the treatment of diseases ranging from cancer and infectious diseases to heritable ...

• Enantioselective Palladium-Catalyzed [3C + 2C] and [4C + 3C] Intramolecular Cycloadditions of Alkylidenecyclopropanes 

  Verdugo, Felipe; Villarino, Lara; Durán, Juan; Guliás, Moisés; Mascareñas, José L.; López, Fernando (American Chemical Society, 2018-06-04)

  We report a highly enantioselective [3C + 2C] intramolecular cycloaddition of alkylidenecyclopropanes (ACPs) and alkenes. The best results are obtained by using sterically demanding chiral phosphoramidite ligands derived ...

• Iridium(I)-Catalyzed Intramolecular Cycloisomerization of Enynes: Scope and Mechanistic Course 

  Fernandez, David F.; Rodrigues, Catarina A. B.; Calvelo, Martín; Guliás, Moisés; Mascareñas, José L.; López, Fernando (American Chemical Society, 2018-07-10)

  We report an Ir(I)-catalyzed cycloisomerization methodology that provides access to carbocyclic systems bearing exo-alkene moieties from alkynyl-equipped acyclic precursors. The method relies on the C–H activation of ...

• Recruitment of RNA molecules by connexin RNA-binding motifs: Implication in RNA and DNA transport through microvesicles and exosomes 

  Varela-Eirin, Marta; Varela-Vazquez, Adrian; Rodríguez-Candela Mateos, Marina; Vila-Sanjurjo, Anton; Fonseca, Eduardo; Mascareñas, José L.; Vázquez Sentís, M. Eugenio; Mayan, Maria D. (Elsevier, 2017-04)

  Connexins (Cxs) are integral membrane proteins that form high-conductance plasma membrane channels, allowing communication from cell to cell (via gap junctions) and from cells to the extracellular environment (via ...

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