• Firefly luciferin precursor 2-cyano-6-hydroxybenzothiazole: Fluorescence à la carte controlled by solvent and acidity 

  Jadhav, Ankita S.; Carreira Blanco, Carlos; Fernández Rodríguez, Berta; González Fernández, Sonia; Malkhede, Dipalee D.; Mosquera González, Manuel; Ríos Rodríguez, María del Carmen; Rodríguez-Prieto, Flor (Elsevier, 2020)

  2-Cyano-6-hydroxybenzothiazole (CBTOH) is a key intermediate in the biosynthesis of D-luciferin, also used for its chemical synthesis and as luciferin bioluminescence precursor for chemical analysis. We characterized CBTOH ...

• Organometallic catalysis in aqueous and biological environments: harnessing the power of metal carbenes 

  Gutiérrez Hernández, Sara; Tomás Gamasa, María (Royal Society of Chemistry, 2022)

  Translating the power of transition metal catalysis to the native habitats of enzymes can significantly expand the possibilities of interrogating or manipulating natural biological systems, including living cells and ...

• Palladium-Catalyzed Tandem Cycloisomerization/Cross-Coupling of Carbonyl- and Imine-Tethered Alkylidenecyclopropanes 

  Verdugo Leal, Felipe Ignacio; Rodiño Balboa, Ricardo; Calvelo Souto, Martín; Mascareñas Cid, José Luis; López García, Fernando José (Wiley, 2022)

  A palladium catalytic system is reported for the divergent tandem cycloisomerization and cross-coupling of carbonyl- and imine-tethered alkylidenecyclopropanes (ACPs). The selection of ancillary ligands is pivotal for the ...

• High-yield halide-assisted synthesis of metal–organic framework UiO-based nanocarriers 

  Ceballos Guzmán, Manuel; Cedrún-Morales, Manuela; Rodríguez Pérez, Manuel; Funes-Hernando, Samuel; Vila Fungueiriño, José Manuel; Zampini, Giulia; Polo Tobajas, Ester; Pino, Pablo del; Pelaz García, Beatriz (Royal Society of Chemistry, 2022)

  The synthesis of nanosized metal–organic frameworks (NMOFs) is requisite for their application as injectable drug delivery systems (DDSs) and other biorelevant purposes. Herein, we have critically examined the role of ...

• Aggregation versus inclusion complexes to solubilize drugs with cyclodextrins. A case study using sulphobutylether-β-cyclodextrins and remdesivir 

  Piñeiro Guillén, Ángel; García Fandiño, Rebeca; PIPKIN, JAMES; Antle, Vince (Elsevier, 2021)

  The formation of small hybrid aggregates between excipient and drug molecules is one of the mechanisms that contributes to the solubilization of active principles in pharmaceutical formulations. The characterization of the ...

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