• Exporting Metal-Carbene Chemistry to Live Mammalian Cells: Copper-Catalyzed Intracellular Synthesis of Quinoxalines Enabled by N-H Carbene Insertions 

  Gutiérrez Hernández, Sara; Tomás Gamasa, María; Mascareñas Cid, José Luis (Wiley, 2021)

  Implementing catalytic organometallic transformations in living settings can offer unprecedented opportunities in chemical biology and medicine. Unfortunately, the number of biocompatible reactions so far discovered is ...

• Enantioenriched alpha-Vinyl 1,4-Benzodiazepines and 1,4-Benzoxazepines via Enantioselective Rhodium-Catalyzed Hydrofunctionalizations of Alkynes and Allenes 

  Velasco Rubio, Álvaro; Bernárdez Alfaya, Rodrigo; Varela Carrete, Jesús Ángel; Saá Rodríguez, Carlos (American Chemical Society, 2021)

  Benzofused seven-membered heterocycles such as 1,4-benzo[e]diazepines (1,4-BZDs) and 1,4-benzo[e]oxazepines (1,4-BZOs) were efficiently synthesized by Rh-catalyzed hydrofunctionalization of internal alkynes and allenes in ...

• An Adhesive Peptide from the C-Terminal Domain of α-Synuclein for Single-Layer Adsorption of Nanoparticles onto Substrates 

  Bhak, Ghibom; Méndez Ardoy, Alejandro; Escobedo, Albert; Salvatella, Xavier; Montenegro García, Javier (American Chemical Society, 2020)

  The two-dimensional (2D) homogeneous assembly of nanoparticle monolayer arrays onto a broad range of substrates constitutes an important challenge for chemistry, nanotechnology, and material science. α-Synuclein (αS) is ...

• Sequence Decoding of 1D to 2D Self-Assembling Cyclic Peptides 

  Díaz Arias, Sandra Natalia; Insua López, Ignacio; Bhak, Ghibom; Montenegro García, Javier (Wiley, 2020)

  The inherent ability of peptides to self-assemble with directional and rationally predictable interactions has fostered a plethora of synthetic two-dimensional (2D) supramolecular biomaterials. However, the design of ...

• Short oligoalanine helical peptides for supramolecular nanopore assembly and protein cytosolic delivery 

  Pazo Pascual, Marta; Salluce, Giulia; Lostalé Seijo, Irene; Juanes Carrasco, María Luisa; González García, Francisco; García Fandiño, Rebeca; Montenegro García, Javier (Royal Society of Chemistry, 2021)

  In this work we report a rational design strategy for the identification of new peptide prototypes for the non-disruptive supramolecular permeation of membranes and the transport of different macromolecular giant cargos. ...

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