Recent Submissions

  • Spectroscopic characterization of mitochondrial G-quadruplexes 

    Illodo, Sara; Pérez González, Cibrán; Barcia, Ramiro; Rodriguez-Prieto, Flor ; Al-Soufi, Wajih; Novo Rodríguez, Mercedes (MDPI, 2022)
    Guanine quadruplexes (G4s) are highly polymorphic four-stranded structures formed within guanine-rich DNA and RNA sequences that play a crucial role in biological processes. The recent discovery of the first G4 structures ...
  • The emergence of order: a closer look on peptide assembly and its complexity 

    Méndez Ardoy, Alejandro; Bergueiro Álvarez, Julián; Montenegro García, Javier (2021)
    The self-assembly of peptides and proteins frequently shows structural plasticity depending on subtle alterations. The acquisition of structural data of these peptide assemblies with atomic level precision will be crucial ...
  • (4 + 2) Cycloadditions via Pd C(sp3 )–H activation 

    Vidal Pereira, Xandro; Font, Marc; Cendón Mariño, Borja; Mascareñas Cid, José Luis; Gulías Costa, Moisés (Elsevier, 2021)
    The functionalization of aliphatic C (sp3)-H bonds using Pd catalysis has emerged as a powerful, step economical methodology for the construction of C–C and C–X bonds. Despite the progress in this field, examples of formal ...
  • Pd-Catalyzed Allylic C-H Activation to Seven-Membered N,O-Heterocycles 

    Velasco Rubio, Álvaro; Varela Carrete, Jesús Ángel; Saá Rodríguez, Carlos (Royal Society of Chemistry, 2021)
    Pd-catalyzed allylic C-H activation of simple olefins allows an easy entry to seven-membered N,O-heterocycles such as 1,4-benzoxazepines (1,4-BZOs), 1,4-benzodiazepinones (1,4-BZDs) and 1,4-oxazepanes in good to excellent ...
  • Effect of water models on transmembrane self-assembled cyclic peptide nanotubes 

    Calvelo Souto, Martín; Lynch, Charlotte I.; Granja Guillán, Juan Ramón; Sansom, Mark S. P.; García Fandiño, Rebeca (ACS, 2021)
    Self-assembling cyclic peptide nanotubes can form nanopores when they are inserted in lipid bilayers, acting as ion and/or water permeable channels. In order to improve the versatility of these systems, it is possible to ...

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