Browsing CIQUS-Artigos by Title
Now showing items 10-29 of 408
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Activity of the β-Lactamase inhibitor LN-1-255 against carbapenem-hydrolyzing class D β-lactamases from Acinetobacter baumannii
(American Society for Microbiology, 2017)The number of infections caused by Gram-negative pathogens carrying carbapenemases is increasing, and the group of carbapenem-hydrolyzing class D β-lactamases (CHDLs) is especially problematic. Several clinically important ... -
Advances in lanthanide‐based luminescent peptide probes for monitoring the activity of kinase and phosphatase
(Wiley, 2014)Signaling pathways based on protein phosphorylation and dephosphorylation play critical roles in the orchestration of complex biochemical events and form the core of most signaling pathways in cells (i.e. cell cycle ... -
Aggregation versus inclusion complexes to solubilize drugs with cyclodextrins. A case study using sulphobutylether-β-cyclodextrins and remdesivir
(Elsevier, 2021)The formation of small hybrid aggregates between excipient and drug molecules is one of the mechanisms that contributes to the solubilization of active principles in pharmaceutical formulations. The characterization of the ... -
Allenes and Derivatives in Gold(I)- and Platinum(II)-Catalyzed Formal Cycloadditions
(American Chemical Society, 2019)Conspectus Cycloaddition reactions, by involving the formation of at least two bonds and one cycle in a single operation, represent one of the more practical ways to assemble carbo- and heterocyclic structures from ... -
Amide-Directed Formation of Five-Coordinate Osmium Alkylidenes from Alkynes
(American Chemical Society, 2015-12-31)The amide-directed synthesis of five-coordinate osmium alkylidene derivatives from alkynes is reported. These types of complexes, which have been elusive until now because of the tendency of osmium to give hydride alkylidyne ... -
An Adhesive Peptide from the C-Terminal Domain of α-Synuclein for Single-Layer Adsorption of Nanoparticles onto Substrates
(American Chemical Society, 2020)The two-dimensional (2D) homogeneous assembly of nanoparticle monolayer arrays onto a broad range of substrates constitutes an important challenge for chemistry, nanotechnology, and material science. α-Synuclein (αS) is ... -
An aquaporin 4 antisense oligonucleotide loaded, brain targeted nanoparticulate system design
(Avoxa - Mediengruppe Deutscher Apotheker GmbH, 2014-05)Aquaporins (AQPs), members of the water-channel protein family, are highly expressed in brain tissue especially in astrocytic end-feet. They are important players for water hemostasis during development of cytotoxic as ... -
An on-surface Diels–Alder reaction
(Wiley, 2021)The Diels–Alder reaction is one of the most popular reactions in organic chemistry. However, its use in the field of on-surface synthesis is hampered by the spatial restrictions of this cycloaddition reaction. Herein we ... -
Analysis of the temperature dependence of the thermal conductivity of insulating single crystal oxides
(AIP Publishing LLC, 2016-10)The temperature dependence of the thermal conductivity of 27 different single crystal oxides is reported from ≈20 K to 350 K. These crystals have been selected among the most common substrates for growing epitaxial thin-film ... -
Anharmonicity of Coupled Torsions: The Extended Two-Dimensional Torsion Method and Its Use To Assess More Approximate Methods
(American Chemical Society, 2017-06-30)In this work we present the extended two-dimensional torsion (E2DT) method and use it to analyze the performance of several methods that incorporate torsional anharmonicity more approximately for calculating rotational–vibrational ... -
Anion recognition and induced self-assembly of an alpha,gamma-cyclic peptide to form spherical clusters
(Wiley, 2016-03-21)A cyclic octapeptide composed of hydroxy-functionalized γ-amino acids folds in a "V-shaped" conformation that allows the selective recognition of anions such as chloride, nitrate, and carbonate. The process involves the ... -
Anion Recognition as a Supramolecular Switch of Cell Internalization
(American Chemical Society, 2016)The cell internalization of designed oligoarginine peptides equipped with six glutamic acid residues and an anionic pyranine at the N-terminus is triggered upon addition of a supramolecular host. This host binds specifically ... -
Anomalous and planar Nernst effects in thin films of the half-metallic ferromagnet La2/3Sr1/3 MnO3
(APS Physics, 2014)We report the planar and anomalous Nernst effects in epitaxial thin films of spin polarized La2/3Sr1/3MnO3. The thermal counterpart of the anomalous Hall effect in this material (i.e., the anomalous Nernst effect) shows ... -
Antibiotic adjuvants – A strategy to unlock bacterial resistance to antibiotics
(Elsevier, 2017-08-14)Resistance to available antibiotics in pathogenic bacteria is currently a global challenge since the number of strains that are resistant to multiple types of antibiotics has increased dramatically each year and has spread ... -
Antireflection self-reference method based on ultrathin metallic nanofilms for improving terahertz reflection spectroscopy
(The Optical Society, 2018)We present the potential of an antireflection self-reference method based on ultrathin tantalum nitride (TaN) nanofilms for improving terahertz (THz) reflection spectroscopy. The antireflection self-reference method is ... -
Apparent auxetic to non-auxetic crossover driven by Co2+ redistribution in CoFe2O4 thin films
(AIP Publishing, 2019)Oxide spinels of general formula AB2O4 (A = Mg2+, Fe2+; B = Al3+, Cr3+, etc.) constitute one of the most abundant crystalline structures in mineralogy. In this structure, cations distribute among octahedral and tetrahedral ... -
Aqueous Stable Gold Nanostar/ZIF‐8 Nanocomposites for Light‐Triggered Release of Active Cargo Inside Living Cells
(Wiley, 2019-05-20)A plasmonic core–shell gold nanostar/zeolitic‐imidazolate‐framework‐8 (ZIF‐8) nanocomposite was developed for the thermoplasmonic‐driven release of encapsulated active molecules inside living cells. The nanocomposites were ... -
Assembly of a Ternary Metallopeptide Complex at Specific DNA Sites Mediated by an AT‐Hook Adaptor
(Wiley, 2020)The nickel(II)‐mediated self‐assembly of a multimeric DNA binder is described. The binder is composed of two metal‐chelating peptides derived from a bZIP transcription factor (brHis2) and one short AT‐hook domain equipped ... -
Assembly of Tetrahydroquinolines and 2-Benzazepines by Pd-Catalyzed Cycloadditions Involving the Activation of C(sp3)–H Bonds
(American Chemical Society, 2021)Cycloaddition reactions are among the most practical strategies to assemble cyclic products; however, they usually require the presence of reactive functional groups in the reactants. Here, we report a palladium-catalyzed ... -
Avian reovirus-triggered apoptosis enhances both virus spread and the processing of the viral nonstructural muNS protein
(Elsevier, 2014-08)Avian reovirus non-structural protein muNS is partially cleaved in infected chicken embryo fibroblast cells to produce a 55-kDa carboxyterminal protein, termed muNSC, and a 17-kDa aminoterminal polypeptide, designated ...