Browsing CIQUS-Artigos by Subject "DHQ1 enzyme"
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Hydroxylammonium derivatives for selective active-site lysine modification in the anti-virulence bacterial target DHQ1 enzyme
(Royal Society of Chemistry, 2019)Targeted irreversible inhibitors bearing electrophiles that become activated towards covalent bond formation upon binding to a specific protein/enzyme is an emerging area in drug discovery. Targeting lysine residues is ...