Browsing CIQUS-Artigos by Subject "Dendrimers"
Now showing items 1-6 of 6
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Biodegradable PEG–dendritic block copolymers: synthesis and biofunctionality assessment as vectors of siRNA
(Royal Society of Chemistry, 2017-07-07)One important drawback of most of the currently used dendrimers for biomedical applications is their high stability under physiological conditions that can result in cytotoxicity or complications induced by the accumulation ... -
Dendrimers as Color-Stabilizers of Pyranoanthocyanins: the Dye Concentration Governs the Host-Guest Interaction Mechanisms
(ACS, 2021)Anionic dendrimers have recently emerged as hosts (H) for the color stabilization of the flavylium cation of anthocyanin guests (G). The interaction with a promising, more hydrophobic pyranoanthocyanin illustrates how the ... -
Dendrimers as Innovative Radiopharmaceuticals in Cancer Radionanotherapy
(American Chemical Society, 2016)Radiotherapy is one of the most commonly used cancer treatments, with an estimate of 40% success that could be improved further if more efficient targeting and retention of radiation at the tumor site were achieved. This ... -
Exploring the efficiency of gallic acid-based dendrimers and their block copolymers with PEG as gene carriers
(Future Science, 2012-07-20)The synthesis of a new family of amino-functionalized gallic acid-triethylene glycol (GATG) dendrimers and their block copolymers with polyethylene glycol (PEG) has recently being disclosed. In addition, these dendrimers ... -
Functional Gallic Acid-Based Dendrimers as Synthetic Nanotools to Remodel Amyloid-β-42 into Noncytotoxic Forms
(ACS Publications, 2021)The self-assembly of amyloid-β (Aβ) generates cytotoxic oligomers linked to the onset and progression of Alzheimer’s disease (AD). As many fundamental molecular pathways that control Aβ aggregation are yet to be unraveled, ... -
Tuning the Size of Nanoassembles: A Hierarchical Transfer of Information from Dendrimers to Polyion Complexes
(Wiley, 2018-04-27)The generation of dendrimers is a powerful tool in the control of the size and biodistribution of polyion complexes (PIC). Using a combinatorial screening of six dendrimers (18–243 terminal groups) and five oppositely ...