Now showing items 1-2 of 2

    • Biodegradable PEG–dendritic block copolymers: synthesis and biofunctionality assessment as vectors of siRNA 

      Leiro, Victoria; Garcia, João Pedro; Moreno, Pedro M. D.; Spencer, Ana Patrícia; Fernández Villamarín, Marcos; Riguera Vega, Ricardo; Fernández Megía, Eduardo; Pêgo, Ana Paula (Royal Society of Chemistry, 2017-07-07)
      One important drawback of most of the currently used dendrimers for biomedical applications is their high stability under physiological conditions that can result in cytotoxicity or complications induced by the accumulation ...
    • Synthetic materials at the forefront of gene delivery 

      Lostalé Seijo, Irene; Montenegro García, Javier (Springer Nature, 2018-09-21)
      The delivery of nucleic acids with transient activity for genetic engineering is a promising methodology with potential applications in the treatment of diseases ranging from cancer and infectious diseases to heritable ...





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