Now showing items 1-3 of 3

    • Intracellular Delivery of Biologically-Active Fungal Metabolite Gliotoxin Using Magnetic Nanoparticles 

      Comas, Laura; Polo Tobajas, Ester; Domingo, M. Pilar; Hernández, Yulán; Arias, Maykel; Esteban, Patricia; Martínez-Lostao, Luis; Pardo, Julián; Martínez de la Fuente, Jesús; Gálvez, Eva M. (MDPI, 2019)
      Gliotoxin (GT), a secondary metabolite produced by Aspergillus molds, has been proposed as a potential anti-tumor agent. Here we have developed a nanoparticle approach to enhance delivery of GT in tumor cells and establish ...
    • Magnetically Recyclable Catalytic Carbon Nanoreactors 

      Aygün, Mehtap; Chamberlain, Thomas W.; Giménez López, María del Carmen; Khlobystov, Andrei N. (Wiley, 2018-07-11)
      Multifunctional nanoreactors are assembled using hollow graphitized carbon nanofibers (GNFs) combined with nanocatalysts (Pd or Pt) and magnetic nanoparticles. The latter are introduced in the form of carbon‐coated cobalt ...
    • Novel synthesis of platinum complexes and their intracellular delivery to tumor cells by means of magnetic nanoparticles 

      Quarta, Alessandra; Amorín López, Manuel; Aldegunde Rodríguez, María José; Blasi, Laura; Ragusa, Andrea; Nitti, Simone; Pugliese, Giammarino; Granja Guillán, Juan Ramón; Pellegrino, Teresa (Royal Society of Chemistry, 2019)
      Platinum-based drugs are popular in clinics as chemotherapeutic agents to treat solid tumors. However, severe side effects such as nephro- and neurotoxicity impose strict dosage limitations that can lead to the development ...

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