Browsing CIQUS-Artigos by Title
Now showing items 1-20 of 389
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1,7-Naphthodiyne: a new platform for the synthesis of novel, sterically congested PAHs
(Royal Society of Chemistry, 2016-03-17)The synthesis of an efficient precursor of the novel 1,7-naphthodiyne synthon is reported. Preliminary experiments demonstrate the usefulness of this platform for the synthesis of sterically congested polyarenes, such as ... -
1D to 2D Self Assembly of Cyclic Peptides
(American Chemical Society, 2020)Despite recent developments in two-dimensional self-assembly, most supramolecular 2D materials are assembled by tedious methodologies, with complex surface chemistry and small sizes. We here report d/l-alternating cyclic ... -
[2+1] Cycloaddition of Catalytic Ruthenium Vinyl Carbenes: A Stereoselective Controlled Access to (Z)- and (E)-Vinyl Epoxypyrrolidines
(American Chemical Society, 2016)Aza-alkynals undergo a cyclization reaction with diazo compounds in the presence of catalytic amounts of Cp*RuCl(cod) to afford vinyl epoxypyrrolidines, valuable building blocks for the synthesis of biologically active ... -
(4 + 2) Cycloadditions via Pd C(sp3 )–H activation
(Elsevier, 2021)The functionalization of aliphatic C (sp3)-H bonds using Pd catalysis has emerged as a powerful, step economical methodology for the construction of C–C and C–X bonds. Despite the progress in this field, examples of formal ... -
[4+2] and [4+3] catalytic cycloadditions of allenes
(Royal Society of Chemistry, 2014)This feature review describes the development of catalytic [4+2] and [4+3] cycloadditions of allenes, as efficient and practical methodologies for assembling six and seven-membered cyclic systems. The different methodologies ... -
8‐Aminomethyl‐7‐hydroxy‐4‐methylcoumarins as Multitarget Leads for Alzheimer's Disease
(Wiley, 2016-07-22)This work is part of our ongoing research in the discovery of multitarget therapeutic agents for Alzheimer's disease (AD). A literature screening, based on our recently proposed pharmacophore, led to the identification of ... -
Ab initio investigation of the H2O2 + F elementary reaction
(Elsevier, 2016-07-01) -
Accounting for conformational flexibility and torsional anharmonicity in the H + CH3CH2OH hydrogen abstraction reactions: A multi-path variational transition state theory study
(AIP Publishing, 2014-05-06)This work reports a detailed theoretical study of the hydrogen abstraction reactions from ethanol by atomic hydrogen. The calculated thermal rate constants take into account torsional anharmonicity and conformational ... -
Accurate treatment of two-dimensional non-separable hindered internal rotors
(AIP Publishing, 2013-04-04)This work presents an accurate way for calculating partition functions of strongly coupled hindered rotors in two dimensions. The two-dimensional torsional potential is generated from electronic structure calculations and ... -
Activity of the β-Lactamase inhibitor LN-1-255 against carbapenem-hydrolyzing class D β-lactamases from Acinetobacter baumannii
(American Society for Microbiology, 2017)The number of infections caused by Gram-negative pathogens carrying carbapenemases is increasing, and the group of carbapenem-hydrolyzing class D β-lactamases (CHDLs) is especially problematic. Several clinically important ... -
Advances in lanthanide‐based luminescent peptide probes for monitoring the activity of kinase and phosphatase
(Wiley, 2014)Signaling pathways based on protein phosphorylation and dephosphorylation play critical roles in the orchestration of complex biochemical events and form the core of most signaling pathways in cells (i.e. cell cycle ... -
Allenes and Derivatives in Gold(I)- and Platinum(II)-Catalyzed Formal Cycloadditions
(American Chemical Society, 2019)Conspectus Cycloaddition reactions, by involving the formation of at least two bonds and one cycle in a single operation, represent one of the more practical ways to assemble carbo- and heterocyclic structures from ... -
Amide-Directed Formation of Five-Coordinate Osmium Alkylidenes from Alkynes
(American Chemical Society, 2015-12-31)The amide-directed synthesis of five-coordinate osmium alkylidene derivatives from alkynes is reported. These types of complexes, which have been elusive until now because of the tendency of osmium to give hydride alkylidyne ... -
An Adhesive Peptide from the C-Terminal Domain of α-Synuclein for Single-Layer Adsorption of Nanoparticles onto Substrates
(American Chemical Society, 2020)The two-dimensional (2D) homogeneous assembly of nanoparticle monolayer arrays onto a broad range of substrates constitutes an important challenge for chemistry, nanotechnology, and material science. α-Synuclein (αS) is ... -
An aquaporin 4 antisense oligonucleotide loaded, brain targeted nanoparticulate system design
(Avoxa - Mediengruppe Deutscher Apotheker GmbH, 2014-05)Aquaporins (AQPs), members of the water-channel protein family, are highly expressed in brain tissue especially in astrocytic end-feet. They are important players for water hemostasis during development of cytotoxic as ... -
Analysis of the temperature dependence of the thermal conductivity of insulating single crystal oxides
(AIP Publishing LLC, 2016-10)The temperature dependence of the thermal conductivity of 27 different single crystal oxides is reported from ≈20 K to 350 K. These crystals have been selected among the most common substrates for growing epitaxial thin-film ... -
Anharmonicity of Coupled Torsions: The Extended Two-Dimensional Torsion Method and Its Use To Assess More Approximate Methods
(American Chemical Society, 2017-06-30)In this work we present the extended two-dimensional torsion (E2DT) method and use it to analyze the performance of several methods that incorporate torsional anharmonicity more approximately for calculating rotational–vibrational ... -
Anion recognition and induced self-assembly of an alpha,gamma-cyclic peptide to form spherical clusters
(Wiley, 2016-03-21)A cyclic octapeptide composed of hydroxy-functionalized γ-amino acids folds in a "V-shaped" conformation that allows the selective recognition of anions such as chloride, nitrate, and carbonate. The process involves the ... -
Anion Recognition as a Supramolecular Switch of Cell Internalization
(American Chemical Society, 2016)The cell internalization of designed oligoarginine peptides equipped with six glutamic acid residues and an anionic pyranine at the N-terminus is triggered upon addition of a supramolecular host. This host binds specifically ... -
Anomalous and planar Nernst effects in thin films of the half-metallic ferromagnet La2/3Sr1/3 MnO3
(APS Physics, 2014)We report the planar and anomalous Nernst effects in epitaxial thin films of spin polarized La2/3Sr1/3MnO3. The thermal counterpart of the anomalous Hall effect in this material (i.e., the anomalous Nernst effect) shows ...