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Selective DNA-Binding by Designed Bisbenzamidine-Homeodomain Chimeras
(WILEY-VCH Verlag GmbH, 2014-04-24)
We report the construction of conjugates between three variants of the helix 3 region of a Q50K engrailed homeodomain and bisbenzamidine minor-groove DNA binders. The hybrid featuring the sequence of the native protein ...