Now showing items 21-40 of 76

    • Cytokine thresholds in gingival crevicular fluid with potential diagnosis of chronic periodontitis differentiating by smoking status 

      Arias Bujanda, Nora Adriana; Regueira Iglesias, Alba; Alonso Sampedro, Manuela; González Peteiro, María Mercedes; Mira, Alex; Balsa Castro, Carlos; Tomás Carmona, Inmaculada (Nature Publishing Group, 2018)
      The objective of the present study was to determine cytokine thresholds derived from predictive models for the diagnosis of chronic periodontitis, differentiating by smoking status. Seventy-five periodontally healthy ...
    • Cytokine-based Predictive Models to Estimate the Probability of Chronic Periodontitis: Development of Diagnostic Nomograms 

      Tomás Carmona, Inmaculada; Arias Bujanda, Nora Adriana; Alonso Sampedro, Manuela; Casares de Cal, María Ángeles; Sánchez Sellero, César Andrés; Suárez Quintanilla, David; Balsa Castro, Carlos (Springer Nature, 2017-10-14)
      Although a distinct cytokine profile has been described in the gingival crevicular fluid (GCF) of patients with chronic periodontitis, there is no evidence of GCF cytokine-based predictive models being used to diagnose the ...
    • Deep Neural Networks for Chronological Age Estimation From OPG Images 

      Vila Blanco, Nicolás; Carreira Nouche, María José; Varas Quintana, Paulina; Balsa Castro, Carlos; Tomás Carmona, Inmaculada (IEEE, 2020)
      Chronological age estimation is crucial labour in many clinical procedures, where the teeth have proven to be one of the best estimators. Although some methods to estimate the age from tooth measurements in orthopantomogram ...
    • DenTiUS Plaque, a Web-Based Application for the Quantification of Bacterial Plaque: Development and Usability Study 

      Vila Blanco, Nicolás; Freire Suárez, Vicente; Balsa Castro, Carlos; Tomás Carmona, Inmaculada; Carreira Nouche, María José (JMIR Publications, 2020)
      Background: In the dentistry field, the analysis of dental plaque is vital because it is the main etiological factor in the 2 most prevalent oral diseases: caries and periodontitis. In most of the papers published in the ...
    • Detection of MET Alterations Using Cell Free DNA and Circulating Tumor Cells from Cancer Patients 

      Mondelo Macía, Patricia; Rodríguez López, Carmela; Valiña, Laura; Aguín, Santiago; León Mateos, Luis; García González, Jorge; Abalo, Alicia; Rapado González, Óscar; Suárez Cunqueiro, María Mercedes; Díaz Lagares, Angel; Curiel, Teresa; Calabuig Fariñas, Silvia; Azkárate, Aitor; Obrador Hevia, Antònia; Abdulkader, Ihab; Muinelo Romay, Laura; Díaz Peña, Roberto; López López, Rafael (MDPI, 2020)
      MET alterations may provide a potential biomarker to evaluate patients who will benefit from treatment with MET inhibitors. Therefore, the purpose of the present study is to investigate the utility of a liquid biopsy-based ...
    • Detection of transient bacteraemia following dental extractions by 16S rDNA pyrosequencing: a pilot study 

      Benítez Páez, Alfonso; Álvarez Fernández, Maximiliano; Belda Ferre, Pedro; Rubido Montero, Susana; Mira, Alex; Tomás Carmona, Inmaculada (PLOS, 2013)
      Objective:The current manuscript aims to determine the prevalence, duration and bacterial diversity of bacteraemiafollowing dental extractions using conventional culture-dependent methods and 16S rDNA pyrosequencing.Methods:The ...
    • Development and Characterization of a Tacrolimus/Hydroxypropyl-β-Cyclodextrin Eye Drop 

      García Otero, Xurxo; Díaz Tomé, Victoria; Varela Fernández, Rubén; Martín Pastor, Manuel; González Barcia, Luis Miguel; Blanco Méndez, José; Mondelo García, Cristina; Álvarez Bermúdez, María José; González García, Francisco; Aguiar Fernández, Pablo; Fernández Ferreiro, Anxo; Otero Espinar, Francisco Javier (MDPI, 2021)
      Uveitis is a vision inflammatory disorder with a high prevalence in developing countries. Currently, marketed treatments remain limited and reformulation is usually performed to obtain a tacrolimus eye drop as a therapeutic ...
    • Devices for In situ Development of Non-disturbed Oral Biofilm. A Systematic Review 

      Prada López, Isabel; Quintas González, Víctor; Vilaboa, Carlos; Suárez Quintanilla, David; Tomás Carmona, Inmaculada (Frontiers Media, 2016-06-23)
      Objective: The aim of this review was to assess the types of devices used for in situ development of oral biofilm analyzed microbiologically. Materials and Methods: A systematic search of the literature was conducted ...
    • Diabetes mellitus and oral lichen planus: A systematic review and meta-analysis 

      Mallah, Narmeen; Varela Centelles, Pablo Ignacio; Seoane Romero, Javier; Takkouche, Bahi (Wiley, 2021)
      Objective: To undertake a meta-analysis of the association of Oral Lichen Planus (OLP) with diabetes, two diseases with an important impact on public health and the economy, but the evidence of which about their association ...
    • Diagnostic yield of sentinel lymph node biopsy in oral squamous cell carcinoma T1/T2-N0: systematic review and meta-analysis 

      Mallo Magariños, Manuel; Suárez Ajuria, M.; Marichalar-Mendia, Xabier; Álvarez Calderón, Óscar; Chamorro Petronacci, Cintia Micaela; García García, Abel; Pérez-Sayáns García, Mario (Elsevier, 2021)
      The objective of this study was to conduct a systematic review and meta-analysis on the efficacy of sentinel lymph node biopsy (SLNB) in T1/T2-N0 oral squamous cell carcinoma (OSCC). A systematic review of the literature ...
    • Differential expression of snoRNAs in oral squamous cell carcinomas: new potential diagnostic markers 

      Chamorro Petronacci, Cintia Micaela; Pérez-Sayáns García, Mario; Padín Iruegas, María Elena; Marichalar Mendia, Xabier; Gallas Torreira, Mercedes; García García, Abel (Taylor & Francis, 2018-01-26)
      Background: Small nucleolar RNAs (snoRNAs) are small non-coding RNA sequences whose most studied function is ribosome biogenesis. The altered expression of snoRNA is observed in tumoral processes such as breast cancer and ...
    • Dissecting the proton transport pathway in oral squamous cell carcinoma: state of the art and theranostics implications 

      Lorenzo Pouso, Alejandro Ismael; Pérez-Sayáns García, Mario; Rodríguez Zorrilla, Samuel; Chamorro Petronacci, Cintia Micaela; García García, Abel (MDPI, 2019)
      Cancer cells overexpress proton exchangers at the plasma membrane in order acidify the extracellular matrix and maintain the optimal pH for sustaining cancer growth. Among the families of proton exchangers implicated in ...
    • Effect of chewing an apple on dental plaque removal and on salivary bacterial viability 

      Rubido Montero, Susana; García Caballero, Lucía; Abeleira Pazos, María Teresa; Limeres Posse, Jacobo; García, Marta; Diz Dios, Pedro (Plos, 2018)
      Objectives Studies on dental plaque removal by chewing an apple are scarce and dated, with conflicting findings. This study aimed to determine whether chewing an apple produced mechanical removal of dental plaque or had ...
    • Ex vivo vs. in vivo antibacterial activity of two antiseptics on oral biofilm 

      Prada López, Isabel; Quintas González, Víctor; Casares de Cal, María Ángeles; Suárez Quintanilla, Juan Antonio; Suárez Quintanilla, David; Tomás Carmona, Inmaculada (Frontiers Media, 2015)
      Aim: To compare the immediate antibacterial effect of two application methods (passive immersion and active mouthwash) of two antiseptic solutions on the in situ oral biofilm. Material and Methods: A randomized ...
    • Expression of gingival crevicular fluid markers during early and late healing of intrabony defects after surgical treatment: a systematic review 

      Koidou, V.P.; Chatzopoulos, G.S.; Tomás Carmona, Inmaculada; Nibali, L.; Donos, Nikolaos (Springer, 2019)
      Background: Surgical treatments such as guided tissue regeneration (GTR) and access flap surgery are widely employed for the treatment of intrabony defects. However, little is known regarding the postoperative expression ...
    • Extracellular Vesicles-Based Biomarkers Represent a Promising Liquid Biopsy in Endometrial Cancer 

      Herrero Filgueira, Carolina; Fuente González, Alexandre de la; Casas Arozamena, Carlos; Sebastián, Víctor; Prieto, Martín; Arruebo, Manuel; Abalo, Alicia; Colás, Eva; Moreno Bueno, Gema; Gil Moreno, Antonio; Vilar, Ana; Cueva, Juan; Abal Posada, Miguel; Muinelo Romay, Laura (MDPI, 2019)
      Tumor-derived extracellular vesicles (EVs) are secreted in large amounts into biological fluids of cancer patients. The analysis of EVs cargoes has been associated with patient´s outcome and response to therapy. However, ...
    • Genetic Susceptibility to Periodontal Disease in Down Syndrome: A Case-Control Study 

      Fernández Casado, María; Coo Diz, Alicia de; Quintela García, Inés; García Mato, Eliane; Freitas, Márcio Diniz; Limeres Posse, Jacobo; Diz Dios, Pedro; Blanco Carrión, Juan; Carracedo Álvarez, Ángel María; Cruz Guerrero, Raquel (MDPI, 2021)
      Severe periodontitis is prevalent in Down syndrome (DS). This study aimed to identify genetic variations associated with periodontitis in individuals with DS. The study group was distributed into DS patients with periodontitis ...
    • Global Gene Expression Characterization of Circulating Tumor Cells in Metastasic Castration-Resistant Prostate Cancer Patients 

      León Mateos, Luis; Abalo, Alicia; Casas, Helena; Anido, Urbano; Rapado González, Óscar; Vieito, María; Suárez Cunqueiro, María Mercedes; Gómez Tato, Antonio; Abal Posada, Miguel; López López, Rafael; Muinelo Romay, Laura (MDPI, 2020)
      Background: Current therapeutic options in the course of metastatic castration-resistant prostate cancers (mCRPC) reinforce the need for reliable tools to characterize the tumor in a dynamic way. Circulating tumor cells ...
    • Higher expression of Toll-like receptors 2 and 4 in blood cells of Keratoconus patiens 

      Sobrino Moreiras, Tomás; Regueiro Lorenzo, Uxía; Malfeito Jiménez, María de las Mercedes; Vieites Prado, Alba; Pérez Mato, María; Campos Pérez, Francisco; Lema Gesto, María Isabel (Nature Publishing Group, 2017)
      Inflammation may play a significant role in Keratoconus (KC), but the implication of immunity on this inflammatory response is unknown. Therefore, our aim was to determine the expression levels of Toll-like receptors 2 ...
    • Human salivary microRNAs in Cancer 

      Rapado González, Óscar; Majem, Blanca; Muinelo Romay, Laura; Álvarez Castro, Ana; Santamaría, Anna; Gil Moreno, Antonio; López López, Rafael; Suárez Cunqueiro, María Mercedes (Ivyspring International Publisher, 2018-01-06)
      Circulating microRNAs (miRNAs) have emerged as excellent candidates for cancer biomarkers. Several recent studies have highlighted the potential use of saliva for the identification of miRNAs as novel biomarkers, which ...





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