Recent Submissions

  • Combined Effect of Caspase-Dependent and Caspase-Independent Apoptosis in the Anticancer Activity of Gold Complexes with Phosphine and Benzimidazole Derivatives 

    Rouco Méndez, Lara; Sánchez González, María Ángeles; Alvariño Romero, Rebeca; Alfonso Rancaño, María Amparo; Vázquez López, Ezequiel M.; García Martínez, Emilia; Maneiro Maneiro, Marcelino (MDPI, 2021)
    Since the potential anticancer activity of auranofin was discovered, gold compounds have attracted interest with a view to developing anticancer agents that follow cytotoxic mechanisms other than cisplatin. Two benzimidazole ...
  • Hyaluronan/Poly-L-lysine/Berberine Nanogels for Impaired Wound Healing 

    Amato, Giovanni; Grimaudo, Maria Aurora; Álvarez Lorenzo, Carmen Isabel; Concheiro Nine, Ángel Joaquín; Carbone, Claudia; Bonaccorso, Angela; Puglisi, Giovanni; Musumeci, Teresa (MDPI, 2021)
    Physiological wound healing process can be delayed in the presence of certain pathologies, such as diabetes or cancer. In this perspective, the aim of this study was to design a new nanogel platform of hyaluronan, poly-L-lysine ...
  • Characterization of New Proteomic Biomarker Candidates in Mucopolysaccharidosis Type IVA 

    Álvarez González, José Víctor; Bravo López, Susana Belén; Chantada Vázquez, María del Pilar; Colón Mejeras, Cristóbal; Castro López, María José de; Morales, Montserrat; Vitoria, Isidro; Tomatsu, Shunji; Otero Espinar, Francisco Javier; Couce Pico, María de la Luz (MDPI, 2021)
    Mucopolysaccharidosis type IVA (MPS IVA) is a lysosomal storage disease caused by mutations in the N-acetylgalactosamine-6-sulfatase (GALNS) gene. Skeletal dysplasia and the related clinical features of MPS IVA are caused ...
  • Solvent-Free Processing of Drug-Loaded Poly(ε-Caprolactone) Scaffolds with Tunable Macroporosity by Combination of Supercritical Foaming and Thermal Porogen Leaching 

    Santos Rosales, Víctor; Ardao Palacios, Inés; Goimil García, Leticia; Gómez Amoza, José Luis; García González, Carlos Alberto (MDPI, 2021)
    Demand of scaffolds for hard tissue repair increases due to a higher incidence of fractures related to accidents and bone-diseases that are linked to the ageing of the population. Namely, scaffolds loaded with bioactive ...
  • DSP Toxin Distribution across Organs in Mice after Acute Oral Administration 

    Louzao Ojeda, María Carmen; Abal Camaño, Paula; Costas Sánchez, Celia; Suzuki, Toshiyuki; Watanabe, Ryuichi; Vilariño del Río, Natalia; Botana López, Ana María; Rodríguez Vieytes, María Mercedes; Botana López, Luis Miguel (MDPI, 2021)
    Okadaic acid (OA) and its main structural analogs dinophysistoxin-1 (DTX1) and dinophysistoxin-2 (DTX2) are marine lipophilic phycotoxins distributed worldwide that can be accumulated by edible shellfish and can cause ...

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