• mRNA-activated matrices encoding transcription factors as primers of cell differentiation in tissue engineering 

  Martínez Ledo, Adriana; Senra, Ana; Rilo Álvarez, Héctor; Borrajo Alonso, Erea; Vidal Figueroa, Anxo; Alonso Fernández, María José; García Fuentes, Marcos (Elsevier, 2020)

  Gene-activated matrices (GAMs) encoding pivotal transcription factors (TFs) represent a powerful tool to direct stem cell specification for tissue engineering applications. However, current TF-based GAMs activated with ...

• Artificial intelligence applied to flavonoid data in food matrices 

  Guardado Yordi, Estela; Koelig, Raúl; Matos, Maria J.; Pérez Martínez, Amaury; Caballero, Yailé; Santana Penín, María Lourdes; Pérez Quintana, Manuel; Molina, Enrique; Uriarte Villares, Eugenio (MDPI, 2019)

  Increasing interest in constituents and dietary supplements has created the need for more efficient use of this information in nutrition-related fields. The present work aims to obtain optimal models to predict the total ...

• Surface Plasmon Resonance Biosensor Method for Palytoxin Detection Based on Na+,K+-ATPase Affinity 

  Alfonso Rancaño, María Amparo; Pazos Guldrís, María José; Fernández Araujo, Andrea; Tobío Ageitos, Araceli; Alfonso, Carmen; Rodríguez Vieytes, María Mercedes; Botana López, Luis Miguel (MDPI, 2013)

  Palytoxin (PLTX), produced by dinoflagellates from the genus Ostreopsis was first discovered, isolated, and purified from zoanthids belonging to the genus Palythoa. The detection of this toxin in contaminated shellfish is ...

• Preclinical PET Study of Intravitreal Injections 

  Fernández Ferreiro, Anxo; Luaces Rodríguez, Andrea; Aguiar Fernández, Pablo; Pardo Montero, Juan; González Barcia, Miguel; García Varela, Lara; Herranz, Michel; Silva Rodríguez, Jesús; Gil Martínez, María; Bermúdez Vázquez, María Elvira; Vieites Prado, Alba; Blanco Méndez, José; Lamas Díaz, María Jesús; Gómez-Ulla de Irazazábal, Francisco Javier; Ruibal Morell, Álvaro; Otero Espinar, Francisco Javier; González García, Francisco (The Association for Research in Vision and Ophthalmology, 2017)

  PURPOSE. This work aimed at describing the time course of vitreous clearance through the use of positron emission tomography (PET) as a noninvasive tool for pharmacokinetic studies of intravitreal injection. METHODS. ...

• Through scaffold modification to 3,5-diaryl-4,5-dihydroisoxazoles: new potent and selective inhibitors of monoamine oxidase B 

  Meleddu, Rita; Distinto, Simona; Cirilli, Roberto; Alcaro, Stefano; Yañez Jato, Matilde; Sanna, María Luisa; Corona, Ángela; Melis, Claudia; Bianco, Giulia; Matyus, Peter; Cottiglia, Filippo; Maccioni, Elias (Taylor & Francis, 2017)

  3,5-Diaryl-4,5-dihydroisoxazoles were synthesized and evaluated as monoamine oxidase (MAO) enzyme inhibitors and iron chelators. All compounds exhibited selective inhibitory activity towards the B isoform of MAO in the ...

View more