Browsing FTF-Artigos by Author "5d40c13d-f951-4635-b522-46544c52714e"
Now showing items 1-3 of 3
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A Comprehensive Tyrosine Phosphoproteomic Analysis Reveals Novel Components of the Platelet CLEC-2 Signaling Cascade
Izquierdo Berjano, Irene; Núñez Barrachina, María; Hermida Nogueira, Lidia; Casas, Vanessa; Morán Lara, Luis Arturo; Lacerenza, Serena; Pinto-Llorente, Roberto; Eble, Johannes A.; Ríos, Vivian de los; Domínguez Medina, Eduardo; Loza García, María Isabel; Casal, José Ignacio; Carrascal, Montserrat; Abián, Joaquín; García Alonso, Ángel (Thieme Publishing Group, 2020)C-type lectin-like receptor 2 (CLEC-2) plays a crucial role in different platelet-related physiological and pathological processes. It signals through a tyrosine kinase-mediated pathway that is highly dependent on the ... -
Data on hyper-activation of GPVI signalling inobese patients: towards the identification ofnovel antiplatelet targets in obesity
Núñez Barrachina, María; Berjano Izquierdo, Irene; Hermida Nogueira, Lidia; Sueiro, Aurelio M.; Guitián Fernández, Esteban; Casanueva Freijo, Felipe; Farndale, Richard W.; Masaaki, Moroi; Jung, Stephanie M.; Pardo Pérez, María; García Alonso, Ángel (Elsevier, 2019)This data article is associated with the manuscript "GPVI surface expression and signalling pathway activation are increased in platelets from obese patients: elucidating potential anti-atherothrombotic targets in obesity" ... -
GPVI surface expression and signalling pathway activation are increased in platelets from obese patients: Elucidating potential anti-atherothrombotic targets in obesity
Núñez Barrachina, María; Sueiro, Aurelio M.; Izquierdo Berjano, Irene; Hermida Nogueira, Lidia; Guitián Fernández, Esteban; Casanueva Freijo, Felipe; Farndale, Richard W.; Masaaki, Moroi; Jung, Stephanie M.; Pardo Pérez, María; García Alonso, Ángel (Elsevier, 2019)Background and aims: Platelets play a fundamental role in the increased atherothrombotic risk related to central obesity since they show hyperactivation and lower sensitivity to antiplatelet therapy in obese patients. The ...