Browsing FTF-Artigos by Author "88346dd7-a945-41cc-8f08-f4758e4dfa8d"
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Genetic enhancement of Ras-ERK pathway does not aggravate L-DOPA-induced dyskinesia in mice but prevents the decrease induced by lovastatin
Ruiz DeDiego, Irene; Fasano, Stefania; Solís, Oscar; Garcia Montes, José Rubén; Brea Floriani, José Manuel; Loza García, María Isabel; Brambilla, Riccardo; Moratalla, Rosario (Nature Publishing Group, 2018)Increasing evidence supports a close relationship between Ras-ERK1/2 activation in the striatum and L-DOPA-induced dyskinesia (LID). ERK1/2 activation by L-DOPA takes place through the crosstalk between D1R/AC/PKA/DARPP-32 ...