Browsing FTF-Artigos by Author "a0c943fe-4aa0-4e10-b015-ea65d58ecdee"
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Promising 2,6,9-Trisubstituted Purine Derivatives for Anticancer Compounds: Synthesis, 3D-QSAR, and Preliminary Biological Assays
Salas, Cristian O.; Zarate, Ana Maria; Kryštof, Vladimir; Mella, Jaime; Faundez, Mario; Brea, José Manuel; Loza García, María Isabel; Brito, Ivan; Hendrychová, Denisa; Jorda, Radek; Cabrera, Alan R.; Tapia, Ricardo A.; Espinosa Bustos, Christian (MDPI, 2020)We designed, synthesized, and evaluated novel 2,6,9-trisubstituted purine derivatives for their prospective role as antitumor compounds. Using simple and efficient methodologies, 31 compounds were obtained. We tested these ...