Now showing items 1-11 of 11

    • Antioxidant and neuroprotective potential of the Brown Seaweed Bifurcaria bifurcata in an in vitro Parkinson’s disease model 

      Silva, Joana M.; Alves, Celso; Freitas, Rafaela; Martins, Alice; Pinteus, Susete; Ribeiro, Joana; Gaspar, Helena; Alfonso Rancaño, María Amparo; Pedrosa, Rui (MDPI, 2019)
      Bifurcaria bifurcata is a marine brown seaweed mainly found on the Atlantic coast. Herein, we report the antioxidant and neuroprotective activities of seven fractions (F1–F7) obtained by normal phase chromatography from ...
    • Bromotryptamine and Bromotyramine Derivatives from the Tropical Southwestern Pacific Sponge Narrabeena nigra 

      Miguel Gordo, María; Gegunde Mosquera, Sandra; Calabro, Kevin; Jennings, Laurence K.; Alfonso Rancaño, María Amparo; Genta-Jouve, Grégory; Vacelet, Jean; Botana López, Luis Miguel; Thomas, Olivier P. (MDPI, 2019)
      So far, the Futuna Islands located in the Central Indo-Pacific Ocean have not been inventoried for their diversity in marine sponges and associated chemical diversity. As part of the Tara Pacific expedition, the first ...
    • Evaluation of the impact of mild steaming and heat treatment on the concentration of okadaic acid, dinophysistoxin-2 and dinophysistoxin-3 in mussels 

      Rodríguez Filgueiras, Inés; Alfonso Rancaño, María Amparo; Antelo Queijo, Álvaro; Álvarez, Mercedes; Botana López, Luis Miguel (Multidisciplinary Digital Publishing Institute (MDPI), 2016-06)
      This study explores the effect of laboratory and industrial steaming on mussels with toxin concentrations above and below the legal limit. We used mild conditions for steaming, 100 ˝C for 5 min in industrial processing, ...
    • High serum cyclophilin C levels as a risk factor marker for coronary artery disease 

      Alfonso Rancaño, María Amparo; Bayón Lorenzo, Jeremías; Gegunde Mosquera, Sandra; Alonso López, Eva; Alvariño Romero, Rebeca; Santás Álvarez, Melisa; Testa Fernández, Ana; Ríos Vázquez, Ramón; González Juanatey, Carlos; Botana López, Luis Miguel (Nature Publishing Group, 2019)
      Cyclophilins (Cyps) are ubiquitous proteins that belong to the immunophilins family consistently associated with infammatory and cardiovascular diseases. While levels of CypA have been extensively studied, less data are ...
    • How Safe Is Safe for Marine Toxins Monitoring? 

      Botana López, Luis Miguel; Alfonso Rancaño, María Amparo; Rodríguez Filgueiras, Inés; Botana López, Ana María; Louzao Ojeda, María Carmen; Rodríguez Vieytes, María Mercedes (MDPI AG, 2016-07-06)
      Current regulation for marine toxins requires a monitoring method based on mass spectrometric analysis. This method is pre-targeted, hence after searching for pre-assigned masses, it identifies those compounds that were ...
    • Surface Plasmon Resonance Biosensor Method for Palytoxin Detection Based on Na+,K+-ATPase Affinity 

      Alfonso Rancaño, María Amparo; Pazos Guldrís, María José; Fernández Araujo, Andrea; Tobío Ageitos, Araceli; Alfonso, Carmen; Rodríguez Vieytes, María Mercedes; Botana López, Luis Miguel (MDPI, 2013)
      Palytoxin (PLTX), produced by dinoflagellates from the genus Ostreopsis was first discovered, isolated, and purified from zoanthids belonging to the genus Palythoa. The detection of this toxin in contaminated shellfish is ...
    • Tetrodotoxins Occurrence in Non-Traditional Vectors of the North Atlantic Waters (Portuguese Maritime Territory, and Morocco Coast) 

      Silva, Marisa; Rodríguez Filgueiras, Inés; Barreiro, Aldo; Kaufmann, Manfred; Neto, Ana Isabel; Hassouani, Meryem; Sabour, Brahim; Alfonso Rancaño, María Amparo; Botana López, Luis Miguel; Vasconcelos, Vitor (MDPI, 2019)
      Tetrodotoxin (TTX) is a potent alkaloid typically from tropical ecosystems, but in the last decade its presence has been more pronounced in the temperate waters of the Atlantic. In its last scientific opinion, the European ...
    • The association of bacterial C9-based TTX-like compounds with Prorocentrum minimum opens new uncertainties about shellfish seafood safety 

      Rodríguez Filgueiras, Inés; Alfonso Rancaño, María Amparo; Alonso López, Eva; Rubiolo Gaytán, Juan Andrés; Roel Sánchez, María; Vlamis, Aristidis; Katikou, Panagiota; Jackson, Stephen A; Margassery, Lekha Menon; Dobson, Alan; Botana López, Luis Miguel (Nature Publishing Group, 2017-01)
      In 2012, Tetrodotoxin (TTX) was identified in mussels and linked to the presence of Prorocentrum minimum (P. minimum) in Greece. The connexion between TTX and P. minimum was further studied in this paper. First, the presence ...
    • Yessotoxin, a Marine Toxin, Exhibits AntiAllergic and Anti-Tumoural Activities Inhibiting Melanoma Tumour Growth in a Preclinical Model 

      Tobío Ageitos, Araceli; Alfonso Rancaño, María Amparo; Madera-Salcedo, Iris K.; Botana López, Luis Miguel; Blank, Ulrich (PLOS, 2016-12-14)
      Yessotoxins (YTXs) are a group of marine toxins produced by the dinoflagellates Protoceratium reticulatum, Lingulodinium polyedrum and Gonyaulax spinifera. They may have medical interest due to their potential role as ...
    • Yessotoxin, a promising therapeutic tool 

      Alfonso Rancaño, María Amparo; Rodríguez Vieytes, María Mercedes; Botana López, Luis Miguel (MDPI, 2016-01-28)
      Yessotoxin (YTX) is a polyether compound produced by dinoflagellates and accumulated in filter feeding shellfish. No records about human intoxications induced by this compound have been published, however it is considered ...
    • Zoanthamine alkaloids from the zoantharian zoanthus cf. pulchellus and their effects in neuroinflammation 

      Guillen, Paul O.; Gegunde Mosquera, Sandra; Jaramillo, Karla B.; Alfonso Rancaño, María Amparo; Calabro, Kevin; Alonso López, Eva; Rodriguez, Jenny; Botana López, Luis Miguel; Thomas, Olivier P. (MDPI, 2018)
      Two new zoanthamine alkaloids, namely 3-acetoxynorzoanthamine (1) and 3-acetoxyzoanthamine (2), have been isolated from the zoantharian Zoanthus cf. pulchellus collected off the coast of the Santa Elena Peninsula, Ecuador, ...





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