Now showing items 1-6 of 6

    • Anhydroexfoliamycin, a Streptomyces Secondary Metabolite, Mitigates Microglia-Driven Inflammation 

      Gegunde Mosquera, Sandra; Alfonso Rancaño, María Amparo; Alvariño Romero, Rebeca; Pérez Fuentes, Nadia; Botana López, Luis Miguel (ACS Publications, 2021)
      Anhydroexfoliamycin, a secondary metabolite from Streptomyces, has shown antioxidant properties in primary cortical neurons reducing neurodegenerative hallmarks diseases, both in vitro and in vivo models. Activated microglia, ...
    • Bromotryptamine and Bromotyramine Derivatives from the Tropical Southwestern Pacific Sponge Narrabeena nigra 

      Miguel Gordo, María; Gegunde Mosquera, Sandra; Calabro, Kevin; Jennings, Laurence K.; Alfonso Rancaño, María Amparo; Genta-Jouve, Grégory; Vacelet, Jean; Botana López, Luis Miguel; Thomas, Olivier P. (MDPI, 2019)
      So far, the Futuna Islands located in the Central Indo-Pacific Ocean have not been inventoried for their diversity in marine sponges and associated chemical diversity. As part of the Tara Pacific expedition, the first ...
    • Cyclophilins A, B, and C Role in Human T Lymphocytes Upon Inflammatory Conditions 

      Gegunde Mosquera, Sandra; Alfonso Rancaño, María Amparo; Alvariño Romero, Rebeca; Alonso López, Eva; Botana López, Luis Miguel (Frontiers Media, 2021)
      Cyclophilins (Cyps) are a group of peptidyl-prolyl cis/trans isomerases that play crucial roles in regulatory mechanisms of cellular physiology and pathology in several inflammatory conditions. Their receptor, CD147, also ...
    • High serum cyclophilin C levels as a risk factor marker for coronary artery disease 

      Alfonso Rancaño, María Amparo; Bayón Lorenzo, Jeremías; Gegunde Mosquera, Sandra; Alonso López, Eva; Alvariño Romero, Rebeca; Santás Álvarez, Melisa; Testa Fernández, Ana; Ríos Vázquez, Ramón; González Juanatey, Carlos; Botana López, Luis Miguel (Nature Publishing Group, 2019)
      Cyclophilins (Cyps) are ubiquitous proteins that belong to the immunophilins family consistently associated with infammatory and cardiovascular diseases. While levels of CypA have been extensively studied, less data are ...
    • Single and combined effects of regulated and emerging mycotoxins on viability and mitochondrial function of SH-SY5Y cells 

      Pérez Fuentes, Nadia; Alvariño Romero, Rebeca; Alfonso Rancaño, María Amparo; González Jartín, Jesús María; Gegunde Mosquera, Sandra; Rodríguez Vieytes, María Mercedes; Botana López, Luis Miguel (Elsevier, 2021)
      Co-occurrence of emerging and regulated mycotoxins in contaminated samples has been widely documented, but studies about their combined toxicity are scarce. In this report, the regulated mycotoxins deoxynivalenol, fumonisin ...
    • Zoanthamine alkaloids from the zoantharian zoanthus cf. pulchellus and their effects in neuroinflammation 

      Guillen, Paul O.; Gegunde Mosquera, Sandra; Jaramillo, Karla B.; Alfonso Rancaño, María Amparo; Calabro, Kevin; Alonso López, Eva; Rodriguez, Jenny; Botana López, Luis Miguel; Thomas, Olivier P. (MDPI, 2018)
      Two new zoanthamine alkaloids, namely 3-acetoxynorzoanthamine (1) and 3-acetoxyzoanthamine (2), have been isolated from the zoantharian Zoanthus cf. pulchellus collected off the coast of the Santa Elena Peninsula, Ecuador, ...

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