• Benzopyran-2-ones as attractive scaffold for MAO inhibitors: synthesis, biological evaluation and docking studies 

  Vázquez Rodríguez, Saleta; Matos, Maria João Correia Pinto Carvalho de; Uriarte Villares, Eugenio; Ferino, Giulio; Cadoni, Enzo; Viña Castelao, María Dolores (MDPI, 2011)

  Neurodegenerative diseases are becoming prevalent pathologies in developed societies due to increasing average of life expectancy of the population. This fact has encouraged an active research in the development of new ...

• Synthesis of new phthalazinedione derivatives 

  Munín Doce, Javier; Quezada González, Elías Neftalí; Uriarte Villares, Eugenio; Santana Penín, María Lourdes; Viña Castelao, María Dolores (MDPI, 2011)

  In the past few decades, the synthesis of new heterocyclic compounds has been a subject of great interest due to their wide applicability. Among a large variety of heterocyclic compounds, heterocycles containing phthalazine ...

• Synthesis and pharmacological evaluation of coumarins as new scaffold on the Parkinson´s disease 

  Matos, Maria João Correia Pinto Carvalho de; Viña Castelao, María Dolores; Janeiro, Patricia; Orallo Cambeiro, Francisco; Uriarte Villares, Eugenio; Santana Penín, María Lourdes (MDPI, 2009)

  With the aim to find out the structural features for the MAO inhibitory activity and selectivity, in the present communication we report the design, synthesis and pharmacological evaluation of a new series of 8-bromo-6-m ...

• Design, Synthesis and Pharmacological Evaluation of New Coumarin Derivatives as Monoamine Oxidase A and B Inhibitors 

  Matos, Maria João Correia Pinto Carvalho de; Santana Penín, María Lourdes; Janeiro, Patricia; Quezada González, Elías Neftalí; Uriarte Villares, Eugenio; González Díaz, Humberto; Viña Castelao, María Dolores; Orallo Cambeiro, Francisco (MDPI, 2008)

  With the aim to find out the structural features for the MAO inhibitory activity and selectivity, in the present communication we report the design, synthesis and pharmacological evaluation of a new series of coumarin ...

• Prediction of Neurological Enzyme Targets for Known and New Compounds with a Model using Galvez's Topological Indices 

  Prado Prado, Francisco Javier; González Díaz, Humberto; Sobarzo Sánchez, Eduardo Marcelo; García Pintos, Isela (MDPI, 2015)

  Alzheimer's Disease (AD), Parkinson, and other neurodegenerative diseases are a major health problem nowadays. In this sense, the discovery of new drugs for neurodiseases treatment is a goal of the major importance. Public ...

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