BBM-Artigos
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Self-assembled peptide/polymer hybrid nanoplatform for cancer immunostimulating therapies
(Springer, 2023)Integrating peptide epitopes in self-assembling materials is a successful strategy to obtain nanovaccines with high antigen density and improved efficacy. In this study, self-assembling peptides containing MAGE-A3/PADRE ... -
Clinical spectrum of LMNA-associated type 2 familial partial lipodystrophy: a systematic review
(MDPI, 2023-02-24)Type 2 familial partial lipodystrophy (FPLD2) is a laminopathic lipodystrophy due to pathogenic variants in the LMNA gene. Its rarity implies that it is not well-known. The aim of this review was to explore the published ... -
Effect of β-estradiol on adipogenesis in a 3T3-L1 cell model of prelamin A accumulation
(MDPI, 2024-01-20)The accumulation of farnesylated prelamin A has been suggested as one of the mechanisms responsible for the loss of fat in type 2 familial partial lipodystrophy due to variants in the LMNA gene. In this rare disease, fat ... -
Effects of aluminium on rat brain mitochondria bioenergetics: an in vitro and in vivo study
(Springer, 2017)Numerous studies have highlighted the potential of aluminium as an aetiological factor for some neurodegenerative disorders, particularly Alzheimer’s disease and Parkinson’s disease. Our previous studies have shown that ... -
Association between blood eosinophil count with asthma hospital readmissions
(Elsevier, 2018)Introduction: The presence of eosinophils in asthma inflammation is a relevant factor in the pathophysiology of the disease, however the relationship between the blood eosinophil count (BEC) with asthma severity and prognosis ...