Now showing items 1-2 of 2

    • Blood glutamate EAAT2-cell grabbing therapy in cerebral ischemia 

      Pérez Mato, María; Iglesias Rey, Ramón; Vieites Prado, Alba; Dopico López, Antonio; Argibay González, Bárbara; Fernández Susavila, Héctor; Silva Candal, Andrés da; Pérez Díaz, Amparo; Correa Paz, Clara; Günther, Anne; Ávila Gómez, Paulo; Loza García, María Isabel; Baumann, Arnd; Castillo Sánchez, José Antonio; Sobrino Moreiras, Tomás; Campos Pérez, Francisco (Elsevier, 2019-01)
      Background Excitatory amino acid transporter 2 (EAAT2) plays a pivotal role in glutamate clearance in the adult brain, thereby preventing excitotoxic effects. Considering the high efficacy of EAAT2 for glutamate uptake, ...
    • Shape effect in active targeting of nanoparticles to inflamed cerebral endothelium under static and flow conditions 

      Silva Candal, Andrés da; Brown, Tyler D.; Krishnan, Vinu; López Loureiro, José Ignacio; Ávila Gómez, Paulo; Pusuluri, Anusha; Pérez Díaz, Amparo; Correa Paz, Clara; Hervella Lorenzo, Pablo; Castillo Sánchez, José Antonio; Mitragotri, Samir; Campos Pérez, Francisco (Elsevier, 2019)
      Endothelial cells represent the first biological barrier for compounds, including nanoparticles, administered via the intravascular route. In the case of ischemic stroke and other vascular diseases, the endothelium ...





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