Recent Submissions

  • Kinetic Resolution of Allyltriflamides through a Pd-Catalyzed C–H Functionalization with Allenes: Asymmetric Assembly of Tetrahydropyridines 

    González González, José Manuel; Cendón Mariño, Borja; Mascareñas Cid, José Luis; Gulías Costa, Moisés (American Chemical Society, 2021)
    Enantioenriched, six-membered azacycles are essential structural motifs in many products of pharmaceutical or agrochemical interest. Here we report a simple and practical method for enantioselective assembly of ...
  • Transition Metal‐Promoted Reactions in Aqueous Media and Biological Settings 

    Destito, Paolo; Vidal Vides, Cristian; López García, Fernando; Mascareñas Cid, José Luis (Wiley, 2021)
    During the last decade, there has been a tremendous interest for developing non‐natural biocompatible transformations in biologically relevant media. Among the different encountered strategies, the use of transition metal ...
  • In Silico Study of Coumarins and Quinolines Derivatives as Potent Inhibitors of SARS-CoV-2 Main Protease 

    Yañez, Osvaldo; Osorio, Manuel Isaías; Uriarte Villares, Eugenio; Areche, Carlos; Tiznado, William; Pérez Donoso, José M.; García Beltrán, Olimpio; González Nilo, Fernando (Frontiers, 2021)
    The pandemic that started in Wuhan (China) in 2019 has caused a large number of deaths, and infected people around the world due to the absence of effective therapy against coronavirus 2 of the severe acute respiratory ...
  • Trending Topics on Coumarin and Its Derivatives in 2020 

    Carneiro Viqueira, Aitor; Matos, Maria João Correia Pinto Carvalho de; Uriarte Villares, Eugenio; Santana Penín, María Lourdes (MDPI, 2021)
    Coumarins are naturally occurring molecules with a versatile range of activities. Their structural and physicochemical characteristics make them a privileged scaffold in medicinal chemistry and chemical biology. Many ...
  • Chemical and biological analysis of 4-acyloxy-3-nitrocoumarins as trypanocidal agents 

    Salgado, Francisco J.; Moncada Basualto, Mauricio; Pozo Martínez, Josué; Liempi, Ana; Kemmerling, Ulrike; Maya, Juan Diego; Jaque, Pablo; Borges, Fernanda; Uriarte Villares, Eugenio; Matos, Maria João Correia Pinto Carvalho de; Olea Azar, Claudio (Elsevier, 2021)
    Chagas disease is the most widespread contagious tropical disease in Latin America, being an important public health problem. Treatments against this disease are still very ineffective, presenting several side effects. ...

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