Now showing items 1-2 of 2

    • Supramolecular caging for cytosolic delivery of anionic probes 

      Fernández Caro, Héctor; Lostalé Seijo, Irene; Martínez Calvo, Miguel; Mosquera Mosquera, Jesús; Mascareñas Cid, José Luis; Montenegro García, Javier (Royal Society of Chemistry, 2019)
      The cytosolic delivery of hydrophilic, anionic molecular probes and therapeutics is a major challenge in chemical biology and medicine. Herein, we describe the design and synthesis of peptide–cage hybrids that allow an ...
    • Tuning the properties of penetrating peptides by oxime conjugation 

      Pazo Pascual, Marta; Fernández Caro, Héctor; Priegue Caamaño, Juan Manuel; Lostalé Seijo, Irene; Montenegro García, Javier (Georg Thieme Verlag, 2017-01-25)
      We here describe the application of oxime bond formation between a peptide scaffold and different aldehydes to modify the transporting capabilities of penetrating peptides. We show that bonds such as oximes offer a great ...





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