Now showing items 1-4 of 4

    • Dendrimer mediated clustering of bacteria: improved aggregation and evaluation of bacterial response and viability 

      Leire, Emma; Amaral, Sandra P.; Louzao Pernas, Iria; Winzer, Klaus; Alexander, Cameron; Fernández Megía, Eduardo; Fernández Trillo, Francisco (Royal Society of Chemistry, 2016)
      Here, we evaluate how cationic gallic acid-triethylene glycol (GATG) dendrimers interact with bacteria and their potential to develop new antimicrobials. We demonstrate that GATG dendrimers functionalised with primary ...
    • Hydrazone-modulated peptides for efficient gene transfection 

      Louzao Pernas, Iria; García Fandiño, Rebeca; Montenegro García, Javier (Royal Society of Chemistry, 2017-02-22)
      Gene transfection continues to be a major challenge in chemistry, biology and materials sciences. New methodologies and recent breakthroughs have renewed the interest in the discovery and development of new tools for ...
    • Multipodal dynamic coordination involving cation-π interactions to control the structure of helical polymers 

      Alzubi, Mohammad; Arias, Sandra; Louzao Pernas, Iria; Quiñoá Cabana, Emilio; Riguera Vega, Ricardo; Freire Iribarne, Félix Manuel (Royal Society of Chemistry, 2017-07-06)
      A precise tuning of the four possible states of a helix (P/M helical sense and stretched/compressed helical backbone) is attained by controlling the complexation between Li+ and a poly(phenylacetylene) that bears amide, ...
    • Peptide/Cas9 nanostructures for ribonucleoprotein cell membrane transport and gene edition 

      Lostalé Seijo, Irene; Louzao Pernas, Iria; Juanes Carrasco, María Luisa; Montenegro García, Javier (Royal Society of Chemistry, 2017)
      The discovery of RNA guided endonucleases has emerged as one of the most important tools for gene edition and biotechnology. The selectivity and simplicity of the CRISPR/Cas9 strategy allows the straightforward targeting ...

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