Show simple item record

dc.contributor.authorFaustino, Hélio
dc.contributor.authorVarela Sandá, Iván
dc.contributor.authorMascareñas Cid, José Luis
dc.contributor.authorLópez García, Fernando
dc.date.accessioned2015-04-27T10:58:19Z
dc.date.available2015-04-27T10:58:19Z
dc.date.issued2015-03-02
dc.identifier.citationFaustino, H., Varela, I., Mascareñas Cid, J.L. & López, F. (2015). Gold(I)-catalyzed [2 + 2 + 2] cycloaddition of allenamides, alkenes and aldehydes: a straightforward approach to tetrahydropyrans. "Chemical Science", 6, 2903-2908 [10.1039/C5SC00295H]
dc.identifier.issn2041-6520
dc.identifier.otherE-ISSN 2041-6539
dc.identifier.urihttp://hdl.handle.net/10347/13247
dc.description.abstractAllenamides participate as two-carbon components in an intermolecular [2 + 2 + 2] cycloaddition with alkenes and aldehydes when treated with catalytic amounts of a phosphite gold complex. The reaction is highly regio- and chemoselective, and works with different types of alkenes, including styrenes, enolethers or enamides, as well as with aromatic and aliphatic aldehydes. Accordingly, different types of 2,6- disubstituted tetrahydropyrans can be stereoselectively assembled in a single step from commercial or very accessible starting materials
dc.description.sponsorshipThis work was supported by the Spanish MINECO (SAF2013-41943-R, SAF2010-20822-C02), the ERDF, the European Research Council (Adv. Grant no. 340055) and the Xunta de Galicia (GRC2013-041). HF acknowledges the Fundação para a Ciência e Tecnologia(Portugal) and POPH/FSE for a PhD grant (SFRH/BD/60214/2009)
dc.language.isoeng
dc.publisherRoyal Society of Chemistry
dc.relationinfo:eu-repo/grantAgreement/EC/FP7/340055
dc.relationinfo:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/SAF2013-41943-R/ES/HERRAMIENTAS SINTETICAS EN QUIMICA BIOLOGICA. NUEVAS ESTRATEGIAS MOLECULARES PARA EL TRATAMIENTO Y DIAGNOSTICO DE CANCERES
dc.subjectAllenamides
dc.subjectCycloadditions
dc.subjectAlkenes
dc.subjectAldehydes
dc.subjectTetrahydropyrans
dc.subject.classificationMaterias::Investigación::23 Química::2302 Bioquímica
dc.titleGold(I)-catalyzed [2 + 2 + 2] cycloaddition of allenamides, alkenes and aldehydes: a straightforward approach to tetrahydropyrans
dc.typeinfo:eu-repo/semantics/article
dc.identifier.DOI10.1039/C5SC00295H
dc.relation.publisherversionhttp://dx.doi.org/10.1039/C5SC00295H
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.contributor.affiliationUniversidade de Santiago de Compostela. Centro de Investigación en Química Biolóxica e Materiais Moleculares
dc.contributor.affiliationUniversidade de Santiago de Compostela. Departamento de Química Orgánica


Files in this item

application/pdf
Name: Gold(I)_catalyzed_[2+2+2]_cycloaddition_of_allenamides_alkenes_and_aldehydes.pdf
Size: 724.6 Kb
Format: PDF


Thumbnail

This item appears in the following Collection(s)

Show simple item record






Harvesters:Useful links:
Universidade de Santiago de Compostela | Teléfonos: +34 881 811 000 e +34 982 820 000 | Contact Us | Send Feedback