Studying of lipid profile in very preterm infants, and the effects of different omega-6/omega-3 ratio supplementation
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http://hdl.handle.net/10347/14780
Título: | Studying of lipid profile in very preterm infants, and the effects of different omega-6/omega-3 ratio supplementation
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Autor/a: | Alshweki, Ayham
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Dirección/Titoría: | Couce Pico, María Luz
Leis Trabazo, María Rosaura
Pérez Muñuzuri, Alejandro
Fraga Bermúdez, José María
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Outro/a autor/a: | Universidade de Santiago de Compostela. Facultade de Medicina e Odontoloxía. Departamento de Pediatría
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Palabras chave: | polyunsaturated fatty acids | Nutritional supplementation | newborns <1500 g and/or <32 weeks gestational age | ω-6/ω-3 | |
Data: | 2016-05-23
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Resumo: | Nutritional supplementation with polyunsaturated fatty acids is important in preterm
infants neurodevelopment. This was a randomized trial, in which newborns <1500 g
and/or <32 weeks gestational age were assigned to one of two groups, based on the milk
formula they would receive during the first year of life. Group A were given formula milk
with an ω-6/ω-3 ratio of 2/1, and group B given formula milk with an ω-6/ω-3 ratio of
1/1. Growth, visual-evoked potentials, brainstem auditory-evoked potentials, and plasma
fatty acids were periodically measured, and psychomotor development was assessed
using the Brunet Lézine scale at 24 months. A control group was made up of preterm who
were fed exclusively with breast milk. There were no significant differences in growth or
evoked potentials between the two formula groups. Very preterm infants who received
formula with an ω-6/ω-3 ratio of 2/1 had higher blood levels of essential fatty acids during
the first year, and better psychomotor development at 24 months, compared with very
preterm newborns who consumed formula with an ω-6/ω-3 of 1/1. Therefore, formula
milk with an arachidonic acid quantity double that of docosahexaenoic acid should be
considered for feeding very preterm infants. |
URI: | http://hdl.handle.net/10347/14780
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Dereitos: | Esta obra atópase baixo unha licenza internacional Creative Commons BY-NC-ND 4.0. Calquera forma de reprodución, distribución, comunicación pública ou transformación desta obra non incluída na licenza Creative Commons BY-NC-ND 4.0 só pode ser realizada coa autorización expresa dos titulares, salvo excepción prevista pola lei. Pode acceder Vde. ao texto completo da licenza nesta ligazón: https://creativecommons.org/licenses/by-nc-nd/4.0/deed.gl
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