Show simple item record

dc.contributor.authorPinal Fernández, Diego
dc.contributor.authorZurrón Ocio, Montserrat
dc.contributor.authorDíaz Fernández, Fernando
dc.date.accessioned2017-07-10T08:03:35Z
dc.date.available2017-07-10T08:03:35Z
dc.date.issued2015-11-16
dc.identifier.citationPinal D, Zurrón M, Díaz F (2015) An Event Related Potentials Study of the Effects of Age, Load and Maintenance Duration on Working Memory Recognition. PLoS ONE 10(11): e0143117. https://doi.org/10.1371/journal.pone.0143117
dc.identifier.issn1932-6203
dc.identifier.urihttp://hdl.handle.net/10347/15632
dc.description.abstractAge-related decline in cognitive capacities has been attributed to a generalized slowing of processing speed and a reduction in working memory (WM) capacity. Nevertheless, it is unclear how age affects visuospatial WM recognition and its underlying brain electrical activity. Whether age modulates the effects of memory load or information maintenance duration, which determine the limits of WM, remains also elusive. In this exploratory study, performance in a delayed match to sample task declined with age, particularly in conditions with high memory load. Event related potentials analysis revealed longer N2 and P300 latencies in old than in young adults during WM recognition, which may reflect slowing of stimulus evaluation and classification processes, respectively. Although there were no differences between groups in N2 or P300 amplitudes, the latter was more homogeneously distributed in old than in young adults, which may indicate an age-related increased reliance in frontal vs parietal resources during WM recognition. This was further supported by an age-related reduced posterior cingulate activation and increased superior frontal gyrus activation revealed through standardized low resolution electromagnetic tomography. Memory load and maintenance duration effects on brain activity were similar in both age groups. These behavioral and electrophysiological results add evidence in support of age-related decline in WM recognition theories, with a slowing of processing speed that may be limited to stimulus evaluation and categorization processes -with no effects on perceptual processes- and a posterior to anterior shift in the recruitment of neural resources
dc.description.sponsorshipThis work was financially supported by the Ministerio de Educación (BES 2008-005929) and Ministerio de Economía y Competitividad (PSI2010-22224-C03-03), Gobierno de España; and by the Consellería de Economía e Industria (10 PXIB 211070 PR), and Consellería de Educación e Ordenación Universitaria (Ref: GPC 2014/047), Xunta de Galicia. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript
dc.language.isoeng
dc.publisherPLOS
dc.relationinfo:eu-repo/grantAgreement/MICINN/Plan Nacional de I+D+i 2008-2011/PSI2010-22224-C03-03/ES/ESTUDIO LONGITUDINAL SOBRE MARCADORES PSICOFISIOLOGICOS EN EL ENVEJECIMIENTO NORMAL, DETERIORO COGNITIVO LIGERO Y ENFERMEDAD DE ALZHEIMER
dc.rights© 2015 Pinal et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
dc.titleAn Event Related Potentials Study of the Effects of Age, Load and Maintenance Duration on Working Memory Recognition
dc.typeinfo:eu-repo/semantics/article
dc.identifier.DOI10.1371/journal.pone.0143117
dc.relation.publisherversionhttps://doi.org/10.1371/journal.pone.0143117
dc.type.versioninfo:eu-repo/semantics/publishedVersion
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.contributor.affiliationUniversidade de Santiago de Compostela. Departamento de Psicoloxía Clínica e Psicobioloxía
dc.description.peerreviewedSI


Files in this item

application/pdf
Name: 2015_pinal_event_related_potentials_pone.PDF
Size: 2.065 Mb
Format: PDF


Thumbnail

This item appears in the following Collection(s)

Show simple item record






Harvesters:Useful links:
Universidade de Santiago de Compostela | Teléfonos: +34 881 811 000 e +34 982 820 000 | Contact Us | Send Feedback