• Sex-biased expression of the TLR7 gene in severe COVID-19 patients: Insights from transcriptomics and epigenomics 

  Gómez Carballa, Alberto; Pardo Seco, Juan Pablo; Pischedda, S.; Rivero Calle, Irene; Butler-Laporte, Guillaume; Richards, J.B.; Viz Lasheras, Sandra; Martinón Torres, Federico; Salas Ellacuriaga, Antonio; GENDRES network, / (Elsevier, 2022)

  There is abundant epidemiological data indicating that the incidence of severe cases of coronavirus disease (COVID-19) is significantly higher in males than females worldwide. Moreover, genetic variation at the X-chromosome ...

• Effectiveness of COVID-19 vaccine booster in the general population and in subjects with comorbidities. A population-based study in Spain 

  Mallah, Narmeen; Pardo Seco, Jacobo José; López Pérez, Luis Ricardo; González Pérez, Juan Manuel; Rosón Calvo, Benigno; Otero Barrós, María Teresa; Durán Parrondo, Carmen; Nartallo Penas, Victoria; Mirás Carballal, Susana; Rodríguez Tenreiro, Carmen; Rivero Calle, Irene; Gómez Carballa, Alberto; Salas Ellacuriaga, Antonio; Martinón Torres, Federico (Elsevier, 2022)

  Background: Research on the effectiveness of COVID-19 booster-based vaccine schedule is ongoing and real-world data on vaccine effectiveness (VE) in comorbid patients are limited. We aimed to estimate booster dose VE against ...

• Epigenetic age estimation in saliva and in buccal cells 

  Ambroa Conde, Adrián; Girón-Santamaría, Lorena; Mosquera Miguel, Ana; Phillips, Christopher Paul; Casares de Cal, María Ángeles; Gómez Tato, Antonio; Álvarez Dios, José Antonio; Puente Vila, María del Carmen de la; Ruiz Ramírez, Jorge; Lareu Huidobro, María Victoria; Freire Aradas, Ana María (Elsevier, 2022)

  Age estimation based on epigenetic markers is a DNA intelligence tool with the potential to provide relevant information for criminal investigations, as well as to improve the inference of age-dependent physical characteristics ...

• A common epigenetic clock from childhood to old age 

  Freire Aradas, Ana María; Girón-Santamaría, Lorena; Mosquera Miguel, Ana; Ambroa Conde, Adrián; Phillips, Christopher Paul; Casares de Cal, María Ángeles; Gómez Tato, Antonio; Álvarez Dios, José Antonio; Aliferi, Anastasia; syndercombe court, denise; Branicki, Wojciech; Laréu, Maviky Victoria (Elsevier, 2022)

  Forensic age estimation is a DNA intelligence tool that forms an important part of Forensic DNA Phenotyping. Criminal cases with no suspects or with unsuccessful matches in searches on DNA databases; human identification ...

• A multi-tissue study of immune gene expression profiling highlights the key role of the nasal epithelium in COVID-19 severity 

  Gómez Carballa, Alberto; Rivero Calle, Irene; Pardo Seco, Jacobo José; Gómez Rial, José; Rivero Velasco, Carmen; Rodríguez Núñez, Nuria; Barbeito Castiñeiras, Gema; Perez Freixo, Hugo; Cebey López, Miriam; Barral Arca, Ruth; Rodríguez-Tenreiro Sánchez, Carmen; Dacosta Urbieta, Ana Isabel; Bello, Xabier; Pischedda, Sara; Currás Tuala, María José; Viz Lasheras, Sandra; Martinón Torres, Federico; Salas Ellacuriaga, Antonio; Gen Covid Study Group (Elsevier, 2022)

  Coronavirus Disease-19 (COVID-19) symptoms range from mild to severe illness; the cause for this differential response to infection remains unknown. Unravelling the immune mechanisms acting at different levels of the ...

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