Membrane-disrupting iridium(III) oligocationic organometallopeptides
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| xmlui.metadata.dc.title: | Membrane-disrupting iridium(III) oligocationic organometallopeptides |
| xmlui.metadata.dc.contributor.author: | Salvadó, Iria Gamba, Ilaria Montenegro García, Javier Martínez Costas, José Manuel Brea Floriani, José Manuel Loza García, María Isabel Vázquez López, Miguel Vázquez Sentís, Marco Eugenio |
| xmlui.metadata.dc.contributor.affiliation: | Universidade de Santiago de Compostela. Centro de Investigación en Química Biolóxica e Materiais Moleculares Universidade de Santiago de Compostela. Departamento de Química Inorgánica Universidade de Santiago de Compostela. Departamento de Química Orgánica |
| xmlui.metadata.dc.date.issued: | 2016-08-19 |
| xmlui.metadata.dc.publisher: | Royal Society of Chemistry |
| xmlui.metadata.dc.identifier.citation: | Salvadó, I, Gamba, I, Montenegro J, Martínez-Costas J, Brea JM, Loza MI, Vázquez López M, Vázquez M.E. Membrane-disrupting iridium(III) oligocationic organometallopeptides. Chem. Commun., 2016,52, 11008-11011. DOI: 10.1039/C6CC05537K |
| xmlui.metadata.dc.description.abstract: | A series of oligoarginine peptide derivatives containing cyclometallated iridium(III) units display remarkable cytotoxicity, comparable to that of cisplatin. In vitro studies with unilamellar vesicles support a membrane-disrupting mechanism of action |
| xmlui.metadata.dc.description: | NOTICE: This is the peer reviewed version of the following article: Salvadó, I, Gamba, I, Montenegro J, Martínez-Costas J, Brea JM, Loza MI, Vázquez López M, Vázquez M.E. Membrane-disrupting iridium(III) oligocationic organometallopeptides. Chem. Commun., 2016,52, 11008-11011. DOI: 10.1039/C6CC05537K. This article may be used for non-commercial purposes in accordance with RSC Terms and Conditions for self-archiving |
| xmlui.metadata.dc.relation.publisherversion: | http://dx.doi.org/10.1039/C6CC05537K |
| xmlui.metadata.dc.identifier.uri: | http://hdl.handle.net/10347/15772 |
| xmlui.metadata.dc.identifier.DOI: | 10.1039/C6CC05537K |
| xmlui.metadata.dc.identifier.issn: | 1359-7345 |
| xmlui.metadata.dc.identifier.e-issn: | 1364-548X |
| xmlui.metadata.dc.rights: | © The Royal Society of Chemistry 2016 |
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