• New Approaches in Nanomedicine for Ischemic Stroke 

  Correa Paz, Clara; Silva Candal, Andrés da; Polo Tobajas, Ester; Parcq, Jerome; Vivien, Denis; Maysinger, Dusica; Pelaz García, Beatriz; Campos Pérez, Francisco (MDPI, 2021)

  Ischemic stroke, caused by the interruption of blood flow to the brain and subsequent neuronal death, represents one of the main causes of disability in developed countries. Therapeutic methods such as recanalization ...

• Weak Interactions in Cocrystals of Isoniazid with Glycolic and Mandelic Acids 

  Álvarez Vidaurre, Raquel; Castiñeiras Campos, Alfonso; Frontera, Antonio; García Santos, María Isabel; Gil, Diego M.; González Pérez, Josefa María; Niclós Gutiérrez, Juan; Torres Iglesias, Rocío (MDPI, 2021)

  This work deals with the preparation of pyridine-3-carbohydrazide (isoniazid, inh) cocrystals with two α-hydroxycarboxylic acids. The interaction of glycolic acid (H2ga) or d,l-mandelic acid (H2ma) resulted in the formation ...

• Deciphering the H-Bonding Preference on Nucleoside Molecular Recognition through Model Copper(II) Compounds 

  Velo Gala, Inmaculada; Barceló Oliver, Miquel; Gil, Diego M.; González Pérez, Josefa María; Campos Castiñeiras; Castiñeiras Campos, Alfonso; Domínguez Martín, Alicia (MDPI, 2021)

  The synthetic nucleoside acyclovir is considered an outstanding model of the natural nucleoside guanosine. With the purpose of deepening on the influence and nature of non-covalent interactions regarding molecular recognition ...

• H-Bonds, π-Stacking and (Water)O-H/π Interactions in (µ4-EDTA)Bis(Imidazole) Dicopper(II) Dihydrate 

  Belmont Sánchez, Jeannette Carolina; García Rubiño, María Eugenia; Frontera, Antonio; González Pérez, Josefa María; Castiñeiras Campos, Alfonso; Niclós Gutiérrez, Juan (MDPI, 2021)

  We synthesized and studied the polymeric compound {[Cu2(µ4-EDTA)(Him)2] 2H2O}n (1). The single-crystal structure is reported along with an in depth characterization of its thermal stability (TGA), spectral properties (FT-IR, ...

• Synthesis and X-ray Diffraction Study of thiosemicarbazone Palladacycles with dppm 

  Rúa Sueiro, Marcos; Munín Cruz, Paula; Reigosa Chamorro, Francisco; Vila Abad, José Manuel; Ortigueira Amor, Juan Manuel (MDPI, 2021)

  Cyclometallated compounds have been extensively studied, in particular those with palladium and platinum. This is because of their possible applications in medicinal chemistry, as anticancer or antimicrobial agents; in ...

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