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dc.contributor.authorAlcalde Cuesta, Fernando
dc.contributor.authorGonzález Sequeiros, Pablo
dc.contributor.authorLozano Rojo, Álvaro
dc.date.accessioned2017-10-20T22:36:45Z
dc.date.available2017-10-20T22:36:45Z
dc.date.issued2017-07
dc.identifier.citationAlcalde Cuesta F, González Sequeiros P, Lozano Rojo Á (2017) Suppressors of selection. PLoS ONE 12(7): e0180549. https://doi.org/10.1371/journal.pone.0180549
dc.identifier.urihttp://hdl.handle.net/10347/15931
dc.description.abstractInspired by recent works on evolutionary graph theory, an area of growing interest in mathematical and computational biology, we present examples of undirected structures acting as suppressors of selection for any fitness value r > 1. This means that the average fixation probability of an advantageous mutant or invader individual placed at some node is strictly less than that of this individual placed in a well-mixed population. This leads the way to study more robust structures less prone to invasion, contrary to what happens with the amplifiers of selection where the fixation probability is increased on average for advantageous invader individuals. A few families of amplifiers are known, although some effort was required to prove it. Here, we use computer aided techniques to find an exact analytical expression of the fixation probability for some graphs of small order (equal to 6, 8 and 10) proving that selection is effectively reduced for r > 1. Some numerical experiments using Monte Carlo methods are also performed for larger graphs and some variants.
dc.description.sponsorshipThis work was supported by the Spanish Ministry of Economy and Competitiveness (Grants MTM2013-46337-C2-2-P and MTM2016-77642-C2-2-P) to FA, PGS, and AL, the Government of Galicia (Grant GPC2015/006), and the European Regional Development Fund. AL was also supported by the Government of Aragón, the European Regional Development Fund (Grant E15 Geometría), and the Defense University Center of Zaragoza (Grant CUD 2015-10)
dc.language.isoeng
dc.publisherPublic Library of Science
dc.relationinfo:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/MTM2013-46337-C2-2-P/ES/ALGEBRA Y GEOMETRIA EN DINAMICA REAL Y COMPLEJA III - DINAMICA DE GROUPOS, GRAFOS Y FOLIACIONES Y SUS APLICACIONES
dc.relationinfo:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/MTM2016-77642-C2-2-P/ES
dc.rights© 2017 Alcalde Cuesta et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.titleSuppressors of selection
dc.typeinfo:eu-repo/semantics/article
dc.identifier.DOI10.1371/journal.pone.0180549
dc.relation.publisherversionhttps://doi.org/10.1371/journal.pone.0180549
dc.type.versioninfo:eu-repo/semantics/publishedVersion
dc.identifier.e-issn1932-6203
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.contributor.affiliationUniversidade de Santiago de Compostela. Departamento de Didácticas Aplicadas
dc.contributor.affiliationUniversidade de Santiago de Compostela. Departamento de Matemáticas
dc.description.peerreviewedSI


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© 2017 Alcalde Cuesta et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
Except where otherwise noted, this item's license is described as  © 2017 Alcalde Cuesta et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited





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